Purslane extract

1. Product Overview & Key Specifications

Purslane Extract is a valuable natural ingredient proven in both in vivo and in vitro experiments to offer anti-UV radiation effects. VPOP3 (Purslane Extract) effectively clears intracellular ROS in HaCaT cells, inhibits apoptosis, and reduces the formation of ROS in UVB-induced zebrafish melanoma cells. These dual actions—UV protection and tyrosinase inhibition—make it a powerful ingredient for whitening and photo-aging defense.

2. Technical Highlights & Critical Parameters

2.1 Purslane Extract Whitening & Protection Data

• Melanogenesis Inhibition: VPOP3 inhibits the activity of Tyrosinase in UVB-induced zebrafish melanoma cells and lipid peroxidation, contributing to its anti-photoaging effects.
• Apoptosis Protection: VPOP3 clears intracellular ROS in HaCaT cells, reducing cell apoptosis, particularly in the later stages of the cell cycle.
• Protection Pathway: VPOP3 inhibits the expression of Bcl-2 and promotes the activation of BAX and CASPASE-3 in the apoptotic pathway, ultimately achieving the effect of inhibiting cell apoptosis.

2.2 Customizable Grade Options

Storage Condition: Avoid light, ventilation, dry, in a sealed space.

3. Mechanism of Action

The core mechanism of Purslane Extract for whitening is Tyrosinase Inhibition. Additionally, it acts as a protector against cellular damage:

• Whitening: Directly inhibits the activity of Tyrosinase, a key enzyme in melanin synthesis.
• Antioxidant/Protection: Clears intracellular ROS and inhibits lipid peroxidation, which protects cells from damage and death induced by UVB.
• Anti-UVB Stress: Modulates the expression of Bcl-2 and BAX in the apoptotic pathway to protect cells against UVB stress.

4. Core Advantages & Market USPs

4.1 Competitive Edge for Your Brand

• Proven Whitening Power: Clinical data confirms significant inhibition of tyrosinase activity.
• Photo-Aging Defense: Dual action of ROS clearance and apoptosis inhibition provides protection against UVB-induced aging.
• Natural Safety: Provides superior safety and traceability for premium cosmetic lines.
• Complete Water Solubility: Simplified formulation process for clear, water-based brightening serums.

5. Formulation Guidelines

• Recommended Use Level: 1% – 5% for 1%-content grades; 0.5% for 5%-content grades.
• Dissolution Advice: Easily dissolved into the aqueous phase.
• Ideal Use: Core active ingredient in dedicated whitening serums, essences, and lotions.

6. Quality Assurance & Regulatory Confidence

We are committed to the highest standards of quality and regulatory compliance.

6.1 Certificate Section

Our quality and safety credentials include:

• COSMOS (Natural and Organic Cosmetic Standard)
• ISO 9001 Quality Management System
• ISO 22000 Food Safety Management System
• HALAL Certification
• IQNET (The International Certification Network)
• Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

7. Recommended Synergistic Combinations

• Purslane Extract + Arbutin/Kojic Acid: Maximize tyrosinase inhibition and overall whitening efficacy.
• Purslane Extract + Niacinamide: Targets multiple pathways for pigmentation and reduces UV-induced redness.

8. Typical Applications & Success Stories

• Industry Validation: Ideal for high-performance whitening products and those requiring UV protective claims.
• Product Categories: Anti-Spot Treatments, Brightening Serums, UV Recovery Essences, Whitening Masks.

9. Scientific Evidence & Literature Support

Based on internal lab summaries, Purslane Extract provides reliable melanogenesis and tyrosinase inhibition:

9.1 Research Abstracts

• Inhibición de la Tirosinasa: Treatment of B16 mouse melanoma cells, stimulated by alpha-MSH, showed that the activity of Tyrosinase was significantly reduced after treatment with different concentrations of VPOP3 (Purslane Extract). This demonstrates that VPOP3 can inhibit Tyrosinase activity, resulting in a whitening effect in B16 melanoma cells.
  • Key Data: Tyrosinase activity decreased in a dose-dependent manner after treatment with VPOP3. The highest dose of VPOP3 showed inhibition comparable to 1.5mM Arbutin.

10. Stability and Safety Data Summary

• Safety Profile: High safety is ensured by stringent quality control and its nature as a plant extract.
• Stability: All liquid grades guarantee a 12-month shelf life when stored under recommended conditions.

11. Frequently Asked Questions

Q1: How does Purslane Extract achieve its whitening effect?

A: It directly inhibits the activity of the Tyrosinase enzyme, which is the primary driver of melanin production.

Q2: Does this ingredient protect against sun damage?

A: Yes. Experiments show it clears ROS and inhibits cell apoptosis induced by UVB radiation, offering cellular protection.

Q3: Which grades contain the concentrated whitening component?

A: All grades are efficacious, but the Flavone grades are generally considered key for functional benefits.

Q4: Is the 5% Flavone grade water-soluble?

A: Yes, all listed grades are water-soluble.

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