La papaína es una enzima proteolítica potente, de origen natural, extraída del fruto crudo de la planta de papaya (Carica papaya). Su eficacia cosmética clave reside en su capacidad para digerir selectivamente las proteínas de queratina muertas en la superficie de la piel, proporcionando una exfoliación suave y no abrasiva. Esto conduce a mejoras inmediatas en la textura, luminosidad y claridad de la piel, convirtiéndola en un activo altamente eficaz y suave para formulaciones dirigidas a la opacidad, la textura irregular y los poros congestionados.
| INCI Name | Papain |
|---|---|
| CAS No. | 9001-73-4 |
| Origin | Extraído del fruto de Carica papaya |
| Appearance | Polvo de amarillo claro a beige pálido |
| Actividad Enzimática | ≥ 1000 U/mg (personalizable) |
| Odor | Suave aroma frutal característico |
| Solubility | Fácilmente soluble en agua, apto para formulaciones acuosas. |
| Recommended Usage | 0.1% – 1% |
| pH Stability | 4.0 – 7.0 |
| Packaging | Bolsas de aluminio o bidones de fibra de 1kg / 5kg / 25kg |
Are your premium exfoliating serums and peels driving high consumer return rates due to acid-induced erythema, stinging, and barrier disruption? For global procurement directors and senior cosmetic formulators, finding a highly effective resurfacing agent that respects sensitive skin types is a critical challenge. The ultimate solution is our High-Activity Papain. Engineered by Shaanxi Huatai Bio-Fine Chemicals Co., Ltd., this premium proteolytic enzyme targets and hydrolyzes dead keratinized cells exclusively, delivering the immediate, visible smoothing of high-concentration chemical acids without aggressively lowering the skin’s pH or triggering inflammatory responses.
In the competitive clinical skincare market, efficacy must be balanced with absolute safety. We lead with robust laboratory and clinical data to guarantee the performance of your exfoliating formulations:
Standardized Proteolytic Activity: Rigorous analytical assays confirm exact unit activity per milligram (USP or FCC units/mg), ensuring consistent, batch-to-batch enzymatic power that dissolves peptide bonds in the stratum corneum.
Clinically Proven Corneocyte Desquamation: Studies demonstrate a highly measurable, rapid increase in the rate of dead cell removal from the skin surface, immediately revealing a smoother, brighter, and more uniform texture.
Validated Low Irritation Potential: Clinical patch testing confirms a drastically lower irritation and sensitization potential compared to similar pH-adjusted AHA (Alpha Hydroxy Acid) products, making it the premier choice for reactive skin types.
For Senior Formulators: Extreme Formulation Compatibility
Master the art of enzymatic stability. While enzymes are notoriously delicate, our premium Papain offers extreme formulation flexibility when engineered correctly. It is fully water-soluble and highly effective within a strict, skin-friendly pH range of 5.0 to 7.0. For maximum stability and prolonged shelf-life, it acts as the ultimate active for trending anhydrous (water-free) formats—such as dry cleansing powders, single-use powder masks, and oil-based balms—where it remains perfectly dormant until activated by water during consumer application. In liquid systems, it integrates effectively with the proper use of chelators (like EDTA) and pH buffers.
For Brand Procurement: The Clean Beauty Top Choice
Modern consumers are actively rejecting harsh chemical peels in favor of microbiome-friendly, gentle alternatives. Sourcing our Papain provides your brand with an instantly recognizable, highly trusted Clean Beauty narrative: a 100% natural extract derived from papaya. It allows your marketing team to confidently claim “AHA-Free Resurfacing,” “Instant Radiance,” and “Sensitive Skin Safe,” positioning your product at the forefront of the holistic, high-performance skincare movement.
| Parameter | Detail |
| Active Content | Measured in Activity Units (e.g., USP or FCC units/mg) |
| Clase de Enzima | Cisteína Proteasa |
| Recommended Dosage | 0.1% – 2.0% (Varies based on unit activity) |
| Solubility | Water soluble |
| Stability | Highly sensitive to pH and temperature |
| Rango de pH Óptimo | 5.0 – 7.0 (varies by formulation) |
Accelerate your product development pipeline with these high-impact, synergistic combinations utilizing our premium active portfolio:
The Ultimate Illuminating Powder Cleanser: Combine Papain + Glabridin. Formulate a water-activated dry cleanser. Papain gently digests the dull, keratinized surface layer, instantly clearing the pathway for Glabridin to penetrate deeply and aggressively halt tyrosinase activity, delivering an unmatched, irritation-free brightening effect.
The Advanced AHA-Free Anti-Aging Balm: Pair Papain + Bakuchiol. The holy grail for sensitive, mature skin. Papain provides the immediate surface smoothing and cell turnover historically achieved by glycolic acid, while Bakuchiol stimulates deep collagen synthesis—delivering dramatic wrinkle reduction with zero retinoid or acid flaking.
The Purifying Enzyme Wash-Off Mask: Utilize Papain + Totarol (or Licochalcone A). Ideal for acne-prone, congested skin. Papain selectively exfoliates to unclog pores and remove debris, while Totarol provides an intense, naturally derived antibacterial shield against C. acnes, and Licochalcone A instantly extinguishes inflammatory redness.
Our state-of-the-art manufacturing facilities strictly adhere to the highest international quality, purity, and environmental standards, ensuring your final products meet global compliance effortlessly. We proudly hold the following pure certifications:
ISO 9001 Quality Management System
ISO 22000 Food Safety Management System
COSMOS (Natural and Organic Cosmetic Standard)
HALAL Certification
IQNET (The International Certification Network)
Do not let harsh chemical acids drive away your sensitive skin consumers or compromise your Clean Beauty integrity. Upgrade your active matrix with the industry standard for gentle, highly effective enzymatic resurfacing.
Ready to revolutionize your exfoliating cleansers, masks, and serums?
Take decisive action to optimize your R&D pipeline today. Contact our B2B technical sales experts to access the complete Technical Dossier (TDS, MSDS, COA, and Clinical Efficacy Reports) and immediately request your high-purity, odorless free sample! Ensure your next product launch delivers the flawless, radiant texture your consumers demand without the burn.
Room 1901, Building 2, Wanda Plaza, Beilin District, Xi'an, Shaanxi.
Email: [email protected]
Phone: +86 17868678161
Copyright © 2026. Shaanxi Huatai Bio-Fine Chemical Co., Ltd. All Rights reserved.