Sodium DNA
The Regenerative Gold: Premium Cosmetic Grade Sodium DNA (PDRN)
In the landscape of advanced bio-tech skincare, Sodium DNA (PDRN) stands as the gold standard for cellular-level repair. Extracted from deep-sea salmon by Shaanxi Huatai Bio-fine Chemical Co., our Sodium DNA is a high-performance active designed for medical-aesthetic and luxury skincare brands aiming to deliver clinical-grade firming and tissue regeneration.
Our competitive edge lies in a refined extraction process that preserves the integrity of long-chain DNA fragments, ensuring maximum biological activity and skin compatibility.
| CAS No. | 9008-33-7 |
|---|---|
| Source | Deep-Sea Salmon Milt |
| Appearance Color | White to Off-white Powder or Granules |
| Key Parameter | High Molecular Weight / DNA Purity ≥ 95% |
| Solubility | Water-Soluble |
1. Technical Specifications & Market Edge
| Technical Attribute | Shaanxi Huatai Premium Standard | Competitive Advantage |
| Material Identity | Polydeoxyribonucleotide (PDRN) | A high-purity, structurally robust regenerative polymer. |
| Biological Source | Deep-Sea Salmon Extract | Exhibits exceptional bio-affinity and structural similarity to human DNA, ensuring seamless cellular uptake. |
| Assay Purity | ≥ 95.0% DNA Content | Industry-leading extraction refinement maximizes clinical efficacy while eliminating impurities. |
| N/P (Nitrogen/Phosphorus) Ratio | 1.5 to 2.0 | Verifies the authentic biological signature and absolute integrity of the nucleotide structure. |
| Heavy Metal Limits | < 10 ppm | Rigorously controlled to guarantee compliance with the strictest global cosmetic safety protocols. |
| Solubility Profile | Fully Water-Soluble | Readily miscible in aqueous phases, making it perfect for crystal-clear serums and hydrogel masks. |
2. Biological Mechanisms of Action
Our Sodium DNA (PDRN) reconstructs compromised tissue through three profound, scientifically validated physiological pathways:
| Action Pathway | Biological Impact |
| Targeted A2A Receptor Engagement | Selectively binds to adenosine A2A receptors on the cell surface, vigorously stimulating fibroblast proliferation while actively suppressing the release of inflammatory cytokines. |
| Nucleotide Salvage & Supplementation | Functions as a direct donor of essential nucleobases, supplying the exact biological “building blocks” required to expedite the repair of degraded or UV-damaged cellular DNA. |
| Microvascular Angiogenesis | Triggers the formation of new capillary networks, drastically optimizing dermal microcirculation to flood the tissue with vital oxygen and restorative nutrients. |
3. Formulation & Processing Directives
| Formulation Parameter | Recommendation | Application Note |
| Standard Inclusion Rate | 0.1% to 1.0% | Highly scalable active baseline for daily regenerative care and premium anti-aging lines. |
| Intensive Clinical Dosage | Up to 2.0% | The targeted therapeutic threshold for specialized post-procedure recovery and severe “SOS” rescue therapies. |
| Target pH Window | 5.5 to 7.5 | Demonstrates maximum molecular stability within slightly acidic to neutral skincare environments. |
| Thermal Processing | Maintain Below 40°C | Highly heat-labile; must be introduced exclusively during the formulation’s final cool-down phase to prevent denaturation. |
| Storage Protocol | Cool, Dry, & Light-Protected | To preserve absolute bioactivity, the raw material must be stored in tightly sealed containers away from direct UV exposure. |
4. Strategic Market Positioning & Ingredient Synergies
Commercial Positioning:
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True DNA-Level Regeneration: Transcends superficial hydration by signaling the dermis to rebuild Type I collagen from the ground up, actively reversing structural ptosis (sagging).
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The Post-Procedure Gold Standard: An absolute clinical necessity for rapidly pacifying and repairing compromised skin following aggressive microneedling, laser resurfacing, or chemical peels.
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Quantifiable Clinical Efficacy: Internal laboratory benchmarks demonstrate a profound 30% surge in epidermal elasticity within a standard 28-day cellular turnover cycle.
High-Performance Synergistic Blends:
| Synergistic Pairing | Targeted Formulation Benefit |
| Sodium DNA + Ectoin | Constructs the ultimate extremolyte shield, merging profound internal tissue repair with extreme external defense against pollution and osmotic stress. |
| Sodium DNA + Ergothioneine | Pairs nucleotide-level regeneration with an elite, mitochondria-targeting oxidative defense network. |
| Sodium DNA + Soluble Collagen | Deploys a comprehensive architectural scaffolding system, dramatically enhancing immediate tissue firmness and long-term elasticity. |
5. Quality Control & Regulatory Compliance
| Compliance Area | Assurance Details |
| Manufacturing Accreditations | Synthesized under uncompromising quality control protocols within ISO 9001, ISO 22000, and HALAL certified facilities. |
| Regulatory Documentation | Fully backed by a comprehensive suite of documents (COA, MSDS, TDS) to seamlessly facilitate global brand registrations and compliance. |
| Ideal Product Formats | The premier active for “Glass Skin” essence waters, regenerative eye treatments, post-operative balms, and intensive firming creams. |
6. Collaborate with Shaanxi Huatai Bio-fine Chemical Co.
Upgrade your clinical and premium skincare lines with our ultra-pure, tissue-regenerating polydeoxyribonucleotides.
| Service Offering | Actionable Step |
| Access Technical Data | Request our complete clinical dossier detailing precise safety analytics, purity profiles, and in-vivo elasticity reports. |
| Evaluate Samples | Claim a complimentary sample to directly formulate with the superior solubility and restorative power of our ≥ 95% Sodium DNA. |
| Bespoke Procurement | Contact our technical sales team for factory-direct bulk pricing and specialized parameter customization for your brand. |
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