• Oil-Soluble Glabridin

Oil-Soluble Glabridin 90%

The Natural Whitening Gold and Potent Tyrosinase Inhibitor

Oil-Soluble Glabridin 90% is a premium whitening active ingredient extracted from the root of Glycyrrhiza glabra. Known in the industry as “whitening gold,” Oil-Soluble Glabridin 90% offers exceptional skin penetration capabilities and highly effective skin brightening. Its core advantages include superior oil solubility for cosmetic formulations, high safety and gentleness without blackthorn irritation, and the ability to inhibit melanin at the source. It is one of the most potent natural inhibitors of tyrosinase currently available for high-end whitening and brightening products.

INCI Name

Glabridin

CAS No.

59870-68-7

Source

Natural Botanical (Licorice Root)

Appearance

White powder

Core Function

Tyrosinase Inhibition, Whitening, Anti-inflammatory, Brightening, Melanin Blocking.

Direct from the Manufacturer: Premium Oil-Soluble Glabridin 90%

Searching for a highly stable, non-crystallizing whitening active for your lipid-based formulations? Partner directly with Shaanxi Huatai Bio-Fine Chemicals Co. As an industry-leading manufacturer of botanical extracts, we specialized in producing premium Oil-Soluble Glabridin 90% (CAS: 59870-68-7), strictly backed by COSMOS, ISO 9001/22000, and HALAL certifications.

Known as the “Whitening Gold,” our 90% purity Glabridin is expertly engineered for seamless integration into cosmetic oils and emulsions, ensuring superior bioavailability without compromising product stability. Skip the middlemen and secure factory-direct pricing, consistent quality, and comprehensive technical support from R&D to commercial production.

1. Product Overview and Market Relevance

Oil-Soluble Glabridin 90% addresses the global demand for safe, natural, and highly effective skin-lightening agents. Unlike many synthetic alternatives, Oil-Soluble Glabridin 90% provides potent results while maintaining a gentle profile suitable for sensitive skin. As a high-purity active, it is the gold standard for luxury whitening serums, creams, and targeted spot treatments.

2. Technical Highlights and Mechanisms of Action

2.1 Whitening Mechanism

  • Tyrosinase Inhibition: Oil-Soluble Glabridin 90% acts deep within the skin’s basal layer to inhibit tyrosinase activity, which blocks the synthesis of melanin.

  • Hydrogen Bonding: Computer molecular docking shows that Oil-Soluble Glabridin 90% binds firmly to the active center of tyrosinase through hydrogen bonds.

  • Melanin Blockade: By “guarding the door” of the tyrosinase active center, it prevents the raw material (tyrosine) from entering the synthesis process, effectively stopping melanin production.

2.2 Cellular Efficacy

  • IC50 Value: In tests on B16-F10 melanoma cells, Oil-Soluble Glabridin 90% demonstrated an IC50 value of 18.36 umol/L.

  • Cell Vitality: Experiments show that Oil-Soluble Glabridin 90% has a measurable impact on the relative cell vitality of B16-F10 cells, correlating with its whitening efficacy.

3. Product Specification and Parameters

The following data represents the standardized specifications for Oil-Soluble Glabridin 90%:

Parameter Specification Detail
Content 90%
Product Form White powder
Solubility Oil-soluble
Suggested Dosage Solubility rate 0.2%
Shelf Life 24 months
Storage Conditions Light-proof, ventilated, dry, and airtight space

4. Stability and Formulation Data

Oil-Soluble Glabridin 90% demonstrates excellent stability across various conditions, ensuring it remains effective in finished cosmetic products.

  • Solubility Stability: Tests involving 2g of Oil-Soluble Glabridin 90% dissolved in 1000g of camellia oil show that the dissolved state remains largely unchanged over time.

  • Temperature Resilience: The ingredient maintains high stability at temperatures ranging from -18 degrees Celsius to 48 degrees Celsius for periods of 10 hours and 24 hours.

Oil-Soluble Glabridin 90%

5. Quality Assurance and Regulatory Confidence

Our quality and safety credentials for Oil-Soluble Glabridin 90% include:

  • COSMOS (Natural and Organic Cosmetic Standard)

  • ISO 9001 Quality Management System

  • ISO 22000 Food Safety Management System

  • HALAL Certification

  • IQNET (The International Certification Network)

  • Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

6. Typical Applications

  • High-End Whitening Serums: Using the high purity of Oil-Soluble Glabridin 90% to target stubborn pigmentation.

  • Brightening Night Creams: Leveraging its deep penetration to restore skin tone during the repair cycle.

  • Targeted Spot Correctors: Utilizing its tyrosinase blocking mechanism for specific hyperpigmented areas.

  • Sun Care Support: Included as an anti-inflammatory and preventive whitening agent to counter UV-induced darkening.

7. Frequently Asked Questions

Q1: Why is Oil-Soluble Glabridin 90% called “whitening gold”?

A: Due to its extreme scarcity in nature, the difficulty of high-purity extraction, and its superior whitening efficacy compared to traditional agents, it carries a high value similar to gold in the cosmetic industry.

Q2: Is Oil-Soluble Glabridin 90% stable in formulations?

A: Yes. As shown in stability tests, Oil-Soluble Glabridin 90% remains stable in oil-based systems across a wide temperature range (from -18 to 48 degrees Celsius).

Q3: Does Oil-Soluble Glabridin 90% cause irritation?

A: No. It is characterized by its gentle and safe nature, making it suitable for formulas designed to avoid blackthorn-type irritation while still providing potent results.

Source our high-purity Oil-Soluble Glabridin 90% for stable, high-efficacy natural whitening, superior tyrosinase inhibition, and advanced clean-label brightening formulations.

🔒 Get Your Technical Dossier: Access TDS, MSDS, COA, and Clinical Efficacy Reports.

🔬 Apply for a Free Sample: Test the stable, high-efficacy whitening power of Oil-Soluble Glabridin 90% today.

📞 Get a Customized Quote: Discuss bulk orders and high-purity specifications.

As a premier Oil-Soluble Glabridin 90% Manufacturer in China, we provide high-purity Cosmetic Grade Oil-Soluble Glabridin 90% designed to empower innovative formulations. Our Oil-Soluble Glabridin 90% factory is dedicated to a consistent Bulk supply of Oil-Soluble Glabridin 90%, serving as a reliable Oil-Soluble Glabridin 90% Wholesaler and Supplier for leading global brands. Whether you are optimizing existing formulas or seeking a competitive Oil-Soluble Glabridin 90% Price for large-scale production, our Oil-Soluble Glabridin 90% Active Ingredients offer the quality and stability your brand deserves. Integrate the finest Oil-Soluble Glabridin 90% Skincare Ingredients into your laboratory today.

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. specializes in advanced Functional Skincare Ingredients, featuring high-purity Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. We offer tailored concentrations (1%–99%) and comprehensive OEM solutions. Our ISO 9001/22000 & COSMOS certified production facilities guarantee premium cosmetic-grade quality for global beauty brands.

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