4-Butylresorcinol
4-Butylresorcinol is an exceptionally effective skin lightening agent known for its superior potency as a Tyrosinase inhibitor. It has been clinically proven to significantly reduce melanin synthesis by inhibiting both Tyrosinase and TRP-1 activity, making it up to 40 times more effective than Kojic Acid in certain tests. It is a safe and high-efficiency solution for treating hyperpigmentation and achieving brighter skin tone.
| INCI Name | 4-Butylresorcinol |
|---|---|
| CAS No. | 18979-61-8 |
| Purity | ≥98% |
| Appearance | White or yellowish powder |
| Core Function | Skin Whitening/Brightening, Highly Potent Tyrosinase and TRP-1 Inhibitor. |
1. Product Overview: The Clinical Gold Standard in Brightening
Shaanxi Huatai Bio-fine Chemical Co. provides premium, high-purity 4-Butylresorcinol—widely recognized as one of the most potent skin-depigmenting agents in the modern cosmetic arsenal. By precisely targeting the core enzymatic machinery of melanogenesis, this ingredient offers rapid, visible results against even the most stubborn hyperpigmentation, including melasma and age-related spots. Its extraordinary potency at trace concentrations makes it the definitive choice for premium, clinical-grade brightening serums and concentrated dark-spot correctors.
Core Features & Primary Benefits:
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Dual-Enzyme Inhibition: Simultaneously deactivates Tyrosinase and TRP-1 (Tyrosinase Related Protein-1), effectively silencing the master regulators of melanin production.
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Industry-Leading Potency: Clinically benchmarked as significantly more powerful (up to 40x) than conventional lightening agents like Kojic Acid.
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Precision Brightening: Provides a targeted, highly effective solution for severe, resistant pigmentation issues that often fail to respond to standard brightening actives.
2. Technical Specifications & Quality Parameters
| Technical Attribute | Shaanxi Huatai Premium Standard | Competitive Advantage |
| Material Identity | 4-Butylresorcinol | High-efficacy melanogenesis inhibitor. |
| Assay Purity | ≥ 98.0% | Refined crystalline structure ensures predictable, professional-grade results. |
| Physical Profile | White to Yellowish Powder | Highly stable for versatile formulation in various cosmetic architectures. |
| Dermal Dosage | 0.1% – 0.3% | High-potency active; requires only minimal inclusion for transformative brightening. |
| Solubility Profile | Lipophilic (Oil-Soluble) | Readily miscible in oil phases, glycerin, or ethanol for seamless dispersion. |
3. Biological Mechanisms of Action
Our 4-Butylresorcinol suppresses hyperpigmentation through three key physiological pathways:
| Action Pathway | Biological Impact |
| Master Tyrosinase Deactivation | Directly binds to the active site of Tyrosinase, the rate-limiting enzyme in melanin synthesis, preventing the production of new pigment. |
| TRP-1 Modulation | Specifically inhibits Tyrosinase-Related Protein-1, further blocking downstream melanin synthesis pathways. |
| Hyperpigmentation Blockade | Effectively interrupts the biochemical cascades that lead to hormonal, UV-induced, and post-inflammatory dark spots. |
4. Formulation & Processing Directives
| Formulation Parameter | Recommendation | Application Note |
| Suggested Dosage | 0.1% – 0.3% | Due to extreme potency, these precise limits must be adhered to for maximum safety and efficacy. |
| Processing Instructions | Lipophilic Dispersion | Must be pre-dissolved completely in the oil phase or suitable solvents (e.g., glycerin/ethanol) before incorporation. |
| Optimal pH Window | 3.0 – 6.0 | Maintains peak structural stability and inhibitory performance within this acidic range. |
| Storage Protocol | Cool, Dry, & Dark | Protect from light and maintain temperatures below 30°C to ensure a full 2-year shelf life. |
5. Strategic Market Positioning & Ingredient Synergies
Commercial Positioning:
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The Clinical Brightening Authority: Positions your brand in the high-performance aesthetic category, offering a quantifiable, science-backed solution for severe pigmentation.
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Cost-Efficient Potency: Its profound activity at trace concentrations provides superior ROI and allows for lean formulation architectures.
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Versatile Luxury: Ideally suited for premium oil-based serums, anhydrous brighteners, and professional clinical-grade spot treatments.
High-Performance Synergistic Blends:
| Synergistic Pairing | Targeted Formulation Benefit |
| 4-Butylresorcinol + Tranexamic Acid | The definitive “Brightening Duo”—combining enzyme inhibition with the blockage of deep-seated melanin signaling. |
| 4-Butylresorcinol + Salicin (BHA Precursor) | Pairs intensive pigment inhibition with gentle surface renewal to rapidly refine skin tone and clarity. |
| 4-Butylresorcinol + Ectoin | Protects the brightened complexion from the inflammation-triggered pigment spikes caused by environmental stress. |
6. Quality Control & Regulatory Compliance
| Compliance Area | Assurance Details |
| Manufacturing Accreditations | Synthesized under uncompromising quality control protocols within ISO 9001, ISO 22000, and HALAL certified facilities. |
| Eco-Ethical Standards | Adheres strictly to COSMOS standards, verifying our materials align with natural and organic cosmetic criteria. |
| Regulatory Documentation | Every batch is supported by a comprehensive technical dossier, including COAs, TDS, and MSDS. |
7. Collaborate with Shaanxi Huatai Bio-fine Chemical Co.
Upgrade your brightening lines with our high-potency 4-Butylresorcinol technology.
| Service Offering | Actionable Step |
| Access Technical Data | Request our complete dossier detailing potency benchmarks, stability analytics, and safety evaluations. |
| Evaluate Samples | Claim a complimentary sample to directly evaluate the high-purity performance of our 4-Butylresorcinol. |
| Bespoke Procurement | Contact our technical sales team for factory-direct bulk pricing and specialized formulation parameter support. |
As a premier 4-Butylresorcinol Manufacturer in China, we provide high-purity Cosmetic Grade 4-Butylresorcinol designed to empower innovative formulations. Our 4-Butylresorcinol factory is dedicated to a consistent Bulk supply of 4-Butylresorcinol, serving as a reliable 4-Butylresorcinol Wholesaler and Supplier for leading global brands. Whether you are optimizing existing formulas or seeking a competitive 4-Butylresorcinol Price for large-scale production, our 4-Butylresorcinol Active Ingredients offer the quality and stability your brand deserves. Integrate the finest 4-Butylresorcinol Skincare Ingredients into your laboratory today.
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