• 리코칼콘 A

리코칼콘 A

강력한 항염 및 항노화 효과를 지닌 칼콘
감초에서 추출한 매우 귀중한 화합물인 리코칼콘 A(LA)는 활성산소(ROS) 수치를 감소시키고, 염증을 억제하며, 항균 작용을 하는 강력한 다기능 성분으로 알려져 있습니다. Staphylococcus aureus. It is essential for advanced anti-aging and sensitive skin formulations.
CAS 번호

58749-22-7

출처

천연 식물 추출물(감초 뿌리/줄기)

외관 색상

갈색을 띤 노란색 가루

주요 효능

노화 방지, 항염, 항균

순도

최대 95% (고순도 분말)

용해도

알코올에 용해됨

직접 공급

직접 소싱은 순도와 안정적인 대량 가격을 보장합니다.

OEM 솔루션

맞춤형 순도, 용매 및 맞춤형 활성 솔루션.

COA 보고서

HPLC, INCI 사양 및 SDS 안전 문서.

ISO 인증

ISO22000 및 COSMOS 품질 관리 표준.

1. 제품 개요 및 주요 사양

리코칼콘 A는 감초 식물에서 발견되는 칼콘 계열 화합물입니다. 당사의 리코칼콘 A는 주로 감초의 뿌리와 줄기에서 추출하는데, 이는 잎과 씨앗보다 리코칼콘 A 함량이 더 높기 때문입니다. 복잡한 구조로 인해 고가이면서 고부가가치 성분입니다. 리코칼콘 A는 염증성 피부 질환 발생을 줄이는 데 효과적인 해결책입니다.

리코칼콘 A

2. 기술적 주요 특징 및 핵심 매개변수

당사는 연구 개발팀이 원활한 제품 개발과 뛰어난 성능을 보장하는 데 필요한 정확한 데이터를 제공합니다.

2.1 리코칼콘 A 핵심 효능

  • 노화 방지 및 활성산소 감소: 리코칼콘 A는 감소시킵니다 ROS(활성산소종) 수치 또한 세포 노화의 주요 요인인 텔로미어 단축을 억제합니다.
  • 항염 작용: LA can inhibit the synthesis of NO (산화질소) 및 iNOS(유도성 산화질소 합성효소)의 발현 COX-2 (Cyclooxygenase-2). This prevents the release of pro-inflammatory factors and reduces the frequency of inflammatory skin issues.
  • Broad Application: Licochalcone A is suitable for combating various skin inflammations, such as pediatric atopic dermatitis and photo-inflammation caused by UV radiation.

2.2 Customizable Grade Options

Content Physical Form 용해도 Recommended Use Level Shelf Life
20% 갈색을 띤 노란색 가루 알코올에 용해됨 0.1% – 2% 24 Months
70% 갈색을 띤 노란색 가루 알코올에 용해됨 0.1% – 2% 24 Months
95% 갈색을 띤 노란색 가루 알코올에 용해됨 0.1% – 2% 24 Months

Storage Condition: Avoid light, ventilation, dry, in a sealed space.

3. Mechanism of Action (MoA)

LA primarily works by downregulating inflammatory pathways and combating oxidative stress at the cellular level. Its mechanism includes:

  1. Reducing ROS Levels that lead to cellular senescence.
  2. Inhibiting the release of pro-inflammatory factors to prevent skin inflammation.
  3. Inhibiting Tyrosinase activity while showing clear inhibition against Staphylococcus aureus.

리코칼콘 A

4. Core Advantages & Market USPs

4.1 Competitive Edge for Your Brand

  • Multi-Functional Power: Simultaneously delivers Anti-Aging, Anti-Inflammatory, and Antibacterial benefits.
  • Targeted Anti-Aging: Directly targets the root cause of aging by reducing ROS and inhibiting telomere shortening.
  • High Purity (up to 95%): Ensures potent efficacy for advanced formulations.
  • Natural Anti-Inflammatory: An excellent natural solution for sensitive, reactive, and acne-prone skin.

5. Formulation Guidelines

  • Recommended Use Level: 0.1% – 2% across all grades.
  • Dissolution Advice: As an alcohol-soluble powder, it should be pre-dissolved in the alcohol or oil phase of the formulation.
  • High Purity Benefits: The 95% purity grade is ideal for highly targeted serums and spot treatments.

6. Quality Assurance & Regulatory Confidence

We are committed to the highest standards of quality and regulatory compliance.

6.1 Certificate Section

Our quality and safety credentials include:

  • COSMOS (Natural and Organic Cosmetic Standard)
  • ISO 9001 Quality Management System
  • ISO 22000 Food Safety Management System
  • HALAL Certification
  • IQNET (The International Certification Network)
  • Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

7. Recommended Synergistic Combinations

  • Licochalcone A + Ceramides: Combines anti-inflammatory repair with skin barrier restoration.
  • Licochalcone A + Niacinamide: Synergistic in combating acne, redness, and inflammation.

8. Typical Applications & Success Stories

  • Industry Validation: Used in high-end derma-cosmetic brands targeting sensitive, acne, and redness-prone skin.
  • Product Categories: Anti-Aging Serums, Sensitive Skin Toners, Anti-Redness Creams, Post-Procedure Care.

9. Scientific Evidence & Literature Support

Based on internal lab summaries, our Licochalcone A provides powerful cellular protection:

9.1 Research Abstracts

  • Anti-Aging and ROS Reduction: High ROS levels are a primary cause of cellular senescence. Compared to the control group, Licochalcone ALA at a concentration of 25 mol/L significantly reduced the ROS level in hADSCs (human adipose-derived stem cells) and suppressed telomere shortening (P < 0.05). This indicates its protective role against aging.

  • Anti-Inflammatory Mechanism: LA reduces the release of pro-inflammatory factors, which helps prevent skin inflammation.
  • Dual Action: LA demonstrates the function of inhibiting tyrosinase activity and exhibits a clear inhibitory effect on Staphylococcus aureus.

10. Stability and Safety Data Summary

  • Safety: Derived from natural licorice, LA is generally well-tolerated and is used in sensitive skin products globally.
  • Stability: All powder grades (20%, 70%, 95%) guarantee a 24-month shelf life when stored under recommended conditions.

11. Frequently Asked Questions (FAQ)

Q1: What is the recommended solvent for dissolving Licochalcone A 95%?

A: All grades of Licochalcone A are alcohol-soluble, making alcohol the primary recommended solvent for pre-dissolution.

Q2: Is Licochalcone A suitable for sensitive skin formulations?

A: Yes. Its primary function as an anti-inflammatory and soothing agent makes it highly suitable for sensitive, irritated, and redness-prone skin products.

Q3: How does Licochalcone A combat aging?

A: It works at the cellular level by reducing harmful ROS (free radicals) and suppressing the factors (P16ink4a) that drive cell senescence and telomere shortening.

Q4: Does Licochalcone A offer preservative benefits?

A: While its primary role is functional, it exhibits inhibitory effects against certain bacteria like Staphylococcus aureus, which contributes to overall formulation integrity.

 

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🔒 기술 자료집을 받으세요: 기술자료자료(TDS), 물질안전자료(MSDS), 분석증명서(COA) 및 안전보고서를 열람하세요.

🔬 무료 샘플을 신청하세요: 지금 바로 리코칼콘 A의 항염 효과를 시험해 보세요.

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Natural huatai는 고순도 글라브리딘(미백), 리코칼콘 A(항여드름), 토타롤, 디포타슘 글리시리제이트를 특징으로 하는 고급 기능성 스킨케어 성분을 전문으로 합니다. 맞춤형 농도(1%–99%)와 포괄적인 OEM 솔루션을 제공합니다. ISO 9001/22000 및 COSMOS 인증 생산 시설은 글로벌 뷰티 브랜드에 프리미엄 화장품 등급 품질을 보장합니다.

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