Azelaic Acid
Azelaic Acid is a naturally occurring dicarboxylic acid celebrated for its potent, multi-action efficacy. It is highly valued for its ability to treat acne and rosacea due to its anti-bacterial, anti-inflammatory, and keratolytic properties. Furthermore, it delivers powerful pigmentation correction by selectively inhibiting hyperactive melanocytes, making it a comprehensive, well-tolerated active for complex skin conditions.
| INCI Name | Azelaic Acid |
|---|---|
| CAS No. | 123-99-9 |
| Source | Natural source (Grains like wheat, rye, barley) or Synthetic |
| Appearance | White crystalline powder |
| Core Function | Anti-acne, Anti-rosacea, Anti-inflammatory, Pigmentation Reduction (Melasma, PIH), Exfoliation |
1. Product Overview: The Clinical Gold Standard for Multi-Action Correction
Shaanxi Huatai Bio-fine Chemical Co. provides premium, 99%-pure Azelaic Acid, a dermatological cornerstone that bridges the gap between cosmetic efficacy and clinical-grade therapeutics. Its unique triple-action mechanism—simultaneously addressing bacterial proliferation, chronic inflammation, and keratinization—makes it the definitive “all-in-one” solution for complex skin concerns. By selectively targeting hyperactive melanocytes and calming the inflammatory pathways typical of rosacea, our high-purity Azelaic Acid empowers brands to deliver rapid, visible results with an industry-leading safety profile.
主な特徴と主な利点：
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Triple-Action Defense: Simultaneously inhibits acne-causing bacteria (P. acnes), reduces systemic inflammation, and normalizes follicular keratinization.
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Selective Pigment Regulation: Intelligently targets hyperactive tyrosinase in abnormal melanocytes to fade melasma and post-inflammatory hyperpigmentation (PIH) without bleaching the surrounding healthy skin.
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Non-Photosensitizing Efficacy: Offers clinical brightening and corrective benefits without increasing sun sensitivity, ensuring it is a safe and robust active for morning and evening application.
技術仕様と品質パラメータ
| 技術的属性 | Shaanxi Huataiプレミアム基準 | 競争優位性 |
| 材料の特定 | Azelaic Acid (Nonanedioic Acid) | High-purity crystalline therapeutic active. |
| アッセイ純度 | ≥ 99.0% | Refined synthesis ensures maximum clinical potency and minimal irritation. |
| Molecular Weight | 188.22 g/mol | Optimized for consistent dermatological penetration. |
| 物理的特性 | White Crystalline Powder | High structural integrity; stable across broad cosmetic architectures. |
| 重金属制限 | < 10 ppm | Adheres to rigorous global safety and toxicological parameters. |
生物学的作用機序
Our Azelaic Acid optimizes skin tone and clarity through four high-precision pathways:
| 作用経路 | 生物学的影響 |
| Anti-Bacterial Inhibition | Directly arrests the growth of Propionibacterium acnes, the master regulator of acne-related inflammation. |
| Keratolytic Normalization | Regulates follicular keratinization, physically unclogging pores and preventing comedone formation. |
| Selective Tyrosinase Blockade | Selectively inhibits hyperactive tyrosinase in abnormal pigment cells, providing effective PIH and melasma resolution. |
| 抗炎症モジュレーション | Scavenges reactive oxygen species and suppresses inflammatory cytokines, providing critical relief for rosacea-associated erythema. |
製剤および加工指示
| 処方パラメータ | 推奨 | Application Note |
| Suggested Dosage | 5.0% – 20.0% | Scalable from cosmetic brightening serums (5–10%) to clinical-grade spot treatments (up to 20%). |
| 加工指示 | Co-Solvent or Hot-Water Dispersion | Due to poor water solubility, it requires either a high-temperature aqueous dispersion (>70°C) or optimized co-solvent systems (e.g., Propylene Glycol). |
| 最適pH範囲 | 4.0～7.0 | Maintains peak structural stability and dermatological comfort within this range. |
| Vehicle Strategy | Emulsion/Cream Suspending | Often formulated into cream or lotion vehicles to suspend crystals effectively for high-dose delivery. |
戦略的な市場ポジショニングと成分の相乗効果
コマーシャルポジショニング：
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The “All-in-One” Corrective: Positions your brand as the authority in addressing acne, redness, and dark spots within a single, elegant product architecture.
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The Clinical Alternative: A high-efficacy, prescription-adjacent active that attracts consumers looking for “dermatologist-strength” results without the dryness or fragility associated with retinoids.
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Day-to-Night Stability: Its non-photosensitizing nature allows for powerful marketing claims regarding 24-hour treatment intensity.
高性能相乗ブレンド：
| 相乗効果のあるペアリング | 標的を絞った製剤の利点 |
| Azelaic Acid + Niacinamide | The definitive “Oil & Tone” complex—balancing sebum production while accelerating PIH clearance. |
| Azelaic Acid + Ectoin | Pairs clinical-grade redness reduction with extreme barrier-soothing protection for rosacea-prone skin. |
| Azelaic Acid + 4-Butylresorcinol | Fuses broad-spectrum pigment suppression with intense, localized tyrosinase-inhibition for stubborn melasma. |
品質管理と規制遵守
| コンプライアンス分野 | 保証の詳細 |
| 製造認証 | 厳格な品質管理プロトコルに従って合成されています。 ISO 9001, ISO 22000, and HALAL 認定施設。 |
| 環境倫理基準 | 厳密に準拠しています。 COSMOS 当社の原材料がナチュラルおよびクリーンラベルの化粧品基準に適合していることを検証する基準。 |
| 規制文書 | 各バッチには、COA、TDS、MSDSを含む包括的な技術文書が付属しています。 |
Shaanxi Huatai Bio-fine Chemical Co.との連携
Upgrade your clinical acne and pigmentation lines with our ultra-pure Azelaic Acid technology.
| サービス提供 | 実行可能なステップ |
| 技術データへのアクセス | Request our complete dossier detailing comparative clinical studies, cytokine-modulation data, and solubility protocols. |
| サンプルの評価 | Claim a complimentary sample to directly evaluate the high-purity crystalline performance of our Azelaic Acid. |
| カスタム調達 | 工場直送のバルク価格および溶媒システム設計に関する専門的なガイダンスについては、テクニカルセールスチームにお問い合わせください。 |
プレミアとして Azelaic Acid 中国のメーカーとして、高純度化粧品グレード製品を提供しています。 Azelaic Acid 革新的な処方を可能にするために設計されています。 Azelaic Acid 工場は、一貫したバルク供給に専念しています。 Azelaic Acid信頼できる Azelaic Acid 世界的な大手ブランドの卸売業者およびサプライヤー。既存の処方を最適化したい場合でも、競争力のある価格を求めている場合でも、 Azelaic Acid 大規模生産の価格、 Azelaic Acid 有効成分は、あなたのブランドにふさわしい品質と安定性を提供します。最高品質の成分を統合 Azelaic Acid スキンケア成分を今すぐあなたの研究室へ。
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