Nicotinamide Mononucleotide, commonly known as NMN, is a naturally occurring nucleotide derived from Vitamin B3 (Niacin). It is widely regarded as one of the most promising anti-aging molecules because it serves as the direct, critical precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme essential for cellular energy metabolism, DNA repair, and Sirtuin (longevity protein) activity. Its key efficacy lies in its ability to boost cellular NAD+ levels, thereby enhancing cell vitality, promoting anti-aging effects, and defending against cellular senescence in both topical and ingestible forms.
| CAS Number | 1094-61-7 |
|---|---|
| Molecular Formula | C₁₁H₁₅N₂O₈P |
| Appearance | White to slightly yellow crystalline powder |
| Purity | ≥99%(detected by HPLC) |
| Plant Source | Microbial Fermentation Method |
| Solubility | Readily soluble in water (10 mg/mL) and PBS buffer; slightly soluble in ethanol (ultrasonic aid needed). |
| Test Report | COA (Please contact us if you need a detailed report) |
| Storage Temperature | Long – term (-20°C, dark): >95% activity/24 months Short – term (2 – 8°C, sealed & dry): >90% activity/6 months |
Nicotinamide Mononucleotide is a leading active in the global longevity and anti-aging market. Consumer awareness of NAD+ decline with age and the corresponding interest in supplementation make Nicotinamide Mononucleotide a high-value, high-demand ingredient. It is positioned as a sophisticated, high-science core active for premium nutraceuticals (capsules, powders) and advanced cosmeceuticals targeting cellular renewal and DNA protection.
NAD+ Synthesis: Nicotinamide Mononucleotide is absorbed by cells and efficiently converted into NAD+, reversing the age-associated decline in NAD+ levels.
Mitochondrial Function: Elevated NAD+ levels support the optimal function of mitochondria (the cell’s powerhouses), boosting cellular energy production and reducing fatigue.
DNA Repair and Longevity: NAD+ is a required cofactor for Sirtuin activity and PARP enzymes, which are critical for repairing damaged DNA and regulating cellular health and longevity pathways.
Skin Vitality: Topically, it can help revitalize aged skin cells, improving overall skin tone, texture, and reducing signs of fatigue.
| Parameter | Detail |
| Purity | 99% minimum (Enzymatic Assay) |
| Recommended Dosage | 100mg – 500mg per day (Oral); 0.5% – 2.0% (Topical) |
| Solubility | Highly water soluble |
| Stability | Generally stable, but sensitive to heat and moisture in solution; best stored cool and dry |
| Optimal ph Range | ph 4.0 – 7.0 |
Science-Driven: Backed by extensive academic research linking NAD+ to aging and longevity.
Direct Precursor: More direct and efficient pathway to boosting NAD+ than basic Vitamin B3 forms.
High Bioavailability: Readily absorbed, with dedicated transporters being studied.
Premium Positioning: A high-value active that commands premium pricing and consumer interest.
Integration Phase: Nicotinamide Mononucleotide is highly water soluble. It should be dissolved in the aqueous phase. To maintain its integrity, it is crucial to avoid high heat and prolonged exposure to high ph environments.
Concentration: Oral dosages must be precisely measured. Topical formulations use it in serums or creams, often requiring advanced stabilization due to its sensitivity in water solution.
Stability: The powder form is highly stable. Finished products (especially liquids) should utilize opaque packaging and require specific stabilizers to maintain shelf life.
Compatibility: Highly compatible with other anti-aging ingredients like Peptides and Hyaluronic Acid.
Our quality and safety credentials include:
COSMOS (Natural and Organic Cosmetic Standard)
ISO 9001 Quality Management System
ISO 22000 Food Safety Management System
HALAL Certification
IQNET (The International Certification Network)
Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)
Longevity and Anti-Aging Supplements: Capsules, sublingual tablets, or powder mixes.
Cellular Energy and Focus Formulas: Combining with ingredients like L-Theanine.
Advanced Cosmeceutical Serums: Targeting skin rejuvenation and vitality.
DNA Repair and Anti-Photoaging Creams: Leveraging its role in cellular maintenance.
NAD+ Conversion Assays: Studies confirm the efficient conversion of Nicotinamide Mononucleotide into NAD+ in various tissues.
Sirtuin Activation: Research demonstrates its ability to enhance the activity of Sirtuin longevity proteins.
Purity Analysis: High-Performance Liquid Chromatography (HPLC) verifies the powder’s purity and concentration.
Q1: What is the difference between Nicotinamide Mononucleotide and Nicotinamide Riboside?
A: Both are effective NAD+ precursors. Nicotinamide Mononucleotide is structurally one step closer to NAD+ than Nicotinamide Riboside in the synthesis pathway, but both are highly utilized by the body to boost NAD+ levels.
Q2: Is Nicotinamide Mononucleotide safe for daily use?
A: Yes. Numerous clinical human trials support the safety and tolerability of Nicotinamide Mononucleotide at recommended oral dosages for daily, long-term consumption.
Q3: Does the topical application penetrate the skin effectively?
A: Research suggests that topical Nicotinamide Mononucleotide can penetrate the skin barrier and deliver benefits to skin cells, making it a viable active for anti-aging skincare products.
Source our high-purity Nicotinamide Mononucleotide Powder for stable, high-efficacy cellular energy boosting, superior NAD+ synthesis, and advanced longevity formulations.
🔒 Get Your Technical Dossier: Access TDS, MSDS, COA, and Clinical Efficacy Reports.
🔬 Apply for a Free Sample: Test the stable, high-efficacy immune-boosting power of Nicotinamide Mononucleotide Powder today.
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En tant que premier ministre NMN Fabricant en Chine, nous fournissons des produits cosmétiques de haute pureté. NMN conçu pour favoriser des formulations innovantes. Notre NMN l'usine est dédiée à un approvisionnement en vrac constant de NMN, servant de fiable NMN Grossiste et fournisseur de grandes marques internationales. Que vous souhaitiez optimiser vos formules existantes ou trouver une solution compétitive, nous avons ce qu'il vous faut. NMN Prix pour une production à grande échelle, notre NMN Les ingrédients actifs offrent la qualité et la stabilité que mérite votre marque. Intégrez les meilleurs ingrédients. NMN Incorporez dès aujourd'hui des ingrédients de soin de la peau à votre laboratoire.
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Email: [email protected]
Phone: +86 17868678161