Azelaic Acid

Azelaic Acid is a naturally occurring dicarboxylic acid celebrated for its potent, multi-action efficacy. It is highly valued for its ability to treat acne and rosacea due to its anti-bacterial, anti-inflammatory, and keratolytic properties. Furthermore, it delivers powerful pigmentation correction by selectively inhibiting hyperactive melanocytes, making it a comprehensive, well-tolerated active for complex skin conditions.

INCI Name

Azelaic Acid

CAS No.

123-99-9

Source

Natural source (Grains like wheat, rye, barley) or Synthetic

Appearance

Weißes kristallines Pulver

Core Function

Anti-acne, Anti-rosacea, Anti-inflammatory, Pigmentation Reduction (Melasma, PIH), Exfoliation

1. Product Overview: The Clinical Gold Standard for Multi-Action Correction

Shaanxi Huatai Bio-fine Chemical Co. provides premium, 99%-pure Azelaic Acid, a dermatological cornerstone that bridges the gap between cosmetic efficacy and clinical-grade therapeutics. Its unique triple-action mechanism—simultaneously addressing bacterial proliferation, chronic inflammation, and keratinization—makes it the definitive “all-in-one” solution for complex skin concerns. By selectively targeting hyperactive melanocytes and calming the inflammatory pathways typical of rosacea, our high-purity Azelaic Acid empowers brands to deliver rapid, visible results with an industry-leading safety profile.

Kernmerkmale & Hauptvorteile:

  • Triple-Action Defense: Simultaneously inhibits acne-causing bacteria (P. acnes), reduces systemic inflammation, and normalizes follicular keratinization.

  • Selective Pigment Regulation: Intelligently targets hyperactive tyrosinase in abnormal melanocytes to fade melasma and post-inflammatory hyperpigmentation (PIH) without bleaching the surrounding healthy skin.

  • Non-Photosensitizing Efficacy: Offers clinical brightening and corrective benefits without increasing sun sensitivity, ensuring it is a safe and robust active for morning and evening application.

Technische Spezifikationen & Qualitätsparameter

Technisches Merkmal Shaanxi Huatai Premium Standard Wettbewerbsvorteil
Identität des Materials Azelaic Acid (Nonanedioic Acid) High-purity crystalline therapeutic active.
Reinheitsgehalt ≥ 99% Refined synthesis ensures maximum clinical potency and minimal irritation.
Molecular Weight 188.22 g/mol Optimized for consistent dermatological penetration.
Physikalisches Profil White Crystalline Powder High structural integrity; stable across broad cosmetic architectures.
Grenzwerte für Schwermetalle < 10 ppm Adheres to rigorous global safety and toxicological parameters.

Biologische Wirkmechanismen

Our Azelaic Acid optimizes skin tone and clarity through four high-precision pathways:

Wirkweg Biologische Auswirkung
Anti-Bacterial Inhibition Directly arrests the growth of Propionibacterium acnes, the master regulator of acne-related inflammation.
Keratolytic Normalization Regulates follicular keratinization, physically unclogging pores and preventing comedone formation.
Selective Tyrosinase Blockade Selectively inhibits hyperactive tyrosinase in abnormal pigment cells, providing effective PIH and melasma resolution.
Entzündungshemmende Modulation Scavenges reactive oxygen species and suppresses inflammatory cytokines, providing critical relief for rosacea-associated erythema.

Formulierungs- & Verarbeitungshinweise

Formulierungsparameter Empfehlung Application Note
Empfohlene Dosierung 5.0% – 20.0% Scalable from cosmetic brightening serums (5–10%) to clinical-grade spot treatments (up to 20%).
Verarbeitungshinweise Co-Solvent or Hot-Water Dispersion Due to poor water solubility, it requires either a high-temperature aqueous dispersion (>70°C) or optimized co-solvent systems (e.g., Propylene Glycol).
Optimales pH-Fenster 4,0 – 7,0 Maintains peak structural stability and dermatological comfort within this range.
Vehicle Strategy Emulsion/Cream Suspending Often formulated into cream or lotion vehicles to suspend crystals effectively for high-dose delivery.

Strategische Marktpositionierung & Inhaltsstoff-Synergien

Kommerzielle Positionierung:

  • The “All-in-One” Corrective: Positions your brand as the authority in addressing acne, redness, and dark spots within a single, elegant product architecture.

  • The Clinical Alternative: A high-efficacy, prescription-adjacent active that attracts consumers looking for “dermatologist-strength” results without the dryness or fragility associated with retinoids.

  • Day-to-Night Stability: Its non-photosensitizing nature allows for powerful marketing claims regarding 24-hour treatment intensity.

Hochleistungs-Synergie-Mischungen:

Synergistische Paarung Gezielter Formulierungsnutzen
Azelaic Acid + Niacinamide The definitive “Oil & Tone” complex—balancing sebum production while accelerating PIH clearance.
Azelaic Acid + Ectoin Pairs clinical-grade redness reduction with extreme barrier-soothing protection for rosacea-prone skin.
Azelaic Acid + 4-Butylresorcinol Fuses broad-spectrum pigment suppression with intense, localized tyrosinase-inhibition for stubborn melasma.

Qualitätskontrolle & regulatorische Konformität

Konformitätsbereich Zusicherungsdetails
Herstellungsakkreditierungen Synthetisiert unter kompromisslosen Qualitätskontrollprotokollen innerhalb ISO 9001, ISO 22000, and HALAL zertifizierten Einrichtungen.
Öko-ethische Standards Hält sich strikt an COSMOS standards, verifying our raw materials align with natural and clean-label cosmetic criteria.
Regulatorische Dokumentation Jede Charge wird durch ein umfassendes technisches Dossier unterstützt, einschließlich COAs, TDS und MSDS.

Arbeiten Sie mit Shaanxi Huatai Bio-fine Chemical Co. zusammen

Upgrade your clinical acne and pigmentation lines with our ultra-pure Azelaic Acid technology.

Serviceangebot Handlungsschritt
Zugriff auf technische Daten Request our complete dossier detailing comparative clinical studies, cytokine-modulation data, and solubility protocols.
Muster bewerten Claim a complimentary sample to directly evaluate the high-purity crystalline performance of our Azelaic Acid.
Maßgeschneiderte Beschaffung Kontaktieren Sie unser technisches Vertriebsteam für Direktvertriebspreise ab Werk und spezialisierte Beratung zu Ihrer Lösungsmittelsystemarchitektur.

Als Premier Azelaic Acid Als Hersteller in China bieten wir hochreine Kosmetikqualität an. Azelaic Acid Entwickelt, um innovative Rezepturen zu ermöglichen. Unsere Azelaic Acid Fabrik ist auf eine gleichbleibende Massenlieferung von spezialisiert Azelaic Acid, dient als zuverlässiger Azelaic Acid Großhändler und Lieferant für führende globale Marken. Ob Sie bestehende Rezepturen optimieren oder eine wettbewerbsfähige Alternative suchen. Azelaic Acid Preis für die Großproduktion, unser Azelaic Acid Aktive Inhaltsstoffe bieten die Qualität und Stabilität, die Ihre Marke verdient. Integrieren Sie die besten Inhaltsstoffe. Azelaic Acid Hautpflegeinhaltsstoffe noch heute in Ihr Labor.

Shaanxi Huatai Bio-Fine Chemicals Co., Ltd. specializes in advanced Functional Skincare Ingredients, featuring high-purity Glabridin (brightening), Licochalcone A (anti-acne), Totarol, and Dipotassium Glycyrrhizinate. We offer tailored concentrations (1%–99%) and comprehensive OEM solutions. Our ISO 9001/22000 & COSMOS certified production facilities guarantee premium cosmetic-grade quality for global beauty brands.

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