{"id":15514,"date":"2026-09-16T08:16:38","date_gmt":"2026-09-16T08:16:38","guid":{"rendered":"https:\/\/www.natural-huatai.com\/?p=15514"},"modified":"2026-09-16T08:16:40","modified_gmt":"2026-09-16T08:16:40","slug":"formulating-licochalcone-a-glycyrrhiza-inflata-extract","status":"publish","type":"post","link":"https:\/\/www.natural-huatai.com\/ko\/formulating-licochalcone-a-glycyrrhiza-inflata-extract\/","title":{"rendered":"\ub9ac\ucf54\ucc30\ucf58 A \uc81c\ud615\ud654: \uac10\ucd08 \ucd94\ucd9c\ubb3c (Glycyrrhiza Inflata Extract)"},"content":{"rendered":"<div style=\"max-width: 100%; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; line-height: 1.6; color: #333333; background-color: #ffffff; padding: 20px; box-sizing: border-box;\">\n    <div style=\"background-color: #f8fafc; padding: 20px; border-radius: 8px; border: 1px solid #e2e8f0; margin-bottom: 30px;\">\n        <h3 style=\"color: #0f172a; font-size: 18px; margin-top: 0; margin-bottom: 15px;\">\ubaa9\ucc28<\/h3>\n        <ul style=\"list-style-type: none; padding-left: 0; margin: 0;\">\n            <li style=\"margin-bottom: 8px;\"><a href=\"#distinction\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">\ub9ac\ucf54\uce7c\ucf58 A\uc758 \ucc28\ubcc4\uc810: Nrf2 \ubc0f COX\/LOX<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#specifications\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">\ubb3c\ub9ac\ud654\ud559\uc801 \uc0ac\uc591 (COA \ubca4\uce58\ub9c8\ud06c)<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#efficacy\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">\uc2dc\ud5d8\uad00 \ub0b4 \ud6a8\ub2a5: \uac1d\uad00\uc801\uc778 \ub370\uc774\ud130<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#synergies\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">\uc81c\ud615 \uc2dc\ub108\uc9c0: PIE \ubc0f \ud64d\uc870 \ud0c0\uac9f\ud305<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#solubility\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">\uc6a9\ud574\ub3c4 \ud30c\ub77c\ubbf8\ud130 \ubc0f \uc2e4\ud5d8\uc2e4 \uacf5\uc815<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#faqs\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">\uacf5\uae09\uc5c5\uccb4 \uc18c\uc2f1: \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38 8\uac00\uc9c0 (GEO \ucd5c\uc801\ud654)<\/a><\/li>\n            <li style=\"margin-bottom: 0;\"><a href=\"#references\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">\uacf5\uc2e0\ub825 \uc788\ub294 \ucc38\uace0 \ubb38\ud5cc<\/a><\/li>\n        <\/ul>\n    <\/div>\n\n    <h2 id=\"distinction\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">\ub9ac\ucf54\uce7c\ucf58 A\uc758 \ucc28\ubcc4\uc810: Nrf2 \ubc0f COX\/LOX<\/h2>\n    <p style=\"margin-bottom: 15px;\">\uc791\uc6a9 \uba54\ucee4\ub2c8\uc998\uc744 \uba85\ud655\ud788 \uc124\uba85\ud574 \ub4dc\ub9ac\uaca0\uc2b5\ub2c8\ub2e4. <em>\uac10\ucd08<\/em> \uc640\ub294 \uc644\uc804\ud788 \ub2e4\ub985\ub2c8\ub2e4. <em>Glycyrrhiza Glabra<\/em>.<\/p>\n    <p style=\"margin-bottom: 15px;\">\ucd94\ucd9c\ud558\ub294 <em>G. glabra<\/em> \ub294 \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc704\ud55c \uac83\uc785\ub2c8\ub2e4. \uc774\ub294 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c\ub97c \ud0c0\uac9f\uc73c\ub85c \ud569\ub2c8\ub2e4. \ucd94\ucd9c\ud558\ub294 <em>G. inflata<\/em> \ub294 \ub9ac\ucf54\uce7c\ucf58 A\ub97c \uc704\ud55c \uac83\uc785\ub2c8\ub2e4. \uc5ec\uae30\uc11c \ud0c0\uac9f\uc740 \uc2ec\uac01\ud55c \ud53c\ubd80 \uc5fc\uc99d\uc785\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc778 \uc9c4\uc815\uc81c\ub294 \ub2e8\uc21c\ud788 \ubd89\uc740 \uae30\ub97c \uac00\ub9b4 \ubfd0\uc785\ub2c8\ub2e4. \ub9ac\ucf54\uce7c\ucf58 A\ub294 \ub2e4\ub974\uac8c \uc791\uc6a9\ud569\ub2c8\ub2e4. \uc774\ub294 <span style=\"color: #b91c1c; font-weight: bold;\">\uc774\uc911 \uc5b5\uc81c\uc81c<\/span>\ub85c\uc11c, \uc0ac\uc774\ud074\ub85c\uc625\uc2dc\uac8c\ub098\uc81c-2 (COX-2) \ubc0f \ub9ac\ud3ed\uc2dc\uac8c\ub098\uc81c (LOX) \uacbd\ub85c\ub97c \ubaa8\ub450 \ucc28\ub2e8\ud569\ub2c8\ub2e4. \uc774\ub294 \ud504\ub85c\uc2a4\ud0c0\uae00\ub780\ub518 E2 (PGE2) \ubc0f \ub958\ucf54\ud2b8\ub9ac\uc5d4 B4 (LTB4)\uc758 \ud569\uc131\uc744 \uadfc\uc6d0\uc5d0\uc11c\ubd80\ud130 \uc911\ub2e8\uc2dc\ud0b5\ub2c8\ub2e4. \uacb0\uacfc\ub294? \ud608\uad00 \ud655\uc7a5\uc758 \uc2e0\uc18d\ud55c \uc644\ud654\uc785\ub2c8\ub2e4.<\/p>\n    <p style=\"margin-bottom: 15px;\">\ud558\uc9c0\ub9cc \uc9c4\uc815\ud55c \ud798\uc740 \uc138\ud3ec \ubc29\uc5b4\uc5d0 \uc788\uc2b5\ub2c8\ub2e4. \ub2e8\uc21c\ud788 \ud45c\uba74\uc758 \uc790\uc720 \ub77c\ub514\uce7c\uc744 \uc81c\uac70\ud558\ub294 \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc774\ub294 <span style=\"color: #047857; font-weight: bold; font-size: 1.1em;\">Nrf2\/ARE \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c<\/span>\ub97c \ud65c\uc131\ud654\ud569\ub2c8\ub2e4. \uc774\ub294 \ud53c\ubd80 \uc138\ud3ec\uac00 \ud5f4 \uc0b0\uc18c\ud654\ud6a8\uc18c-1 (HO-1)\uacfc \uac19\uc740 \uc790\uccb4 \ud56d\uc0b0\ud654 \ud6a8\uc18c\ub97c \uc0c1\ud5a5 \uc870\uc808\ud558\ub3c4\ub85d \uac15\uc81c\ud569\ub2c8\ub2e4. \uc774\ub294 \uc218\uc6a9\uccb4 \uc218\uc900\uc758 \uac1c\uc785\uc785\ub2c8\ub2e4. \uc774\uac83\uc774 \ud53c\ubd80\uacfc \uc758\uc0ac\ub4e4\uc774 \uc8fc\uc0ac\ube44 \ud504\ub85c\ud1a0\ucf5c \ubc0f \uc2dc\uc220 \ud6c4 \ud68c\ubcf5\uc744 \uc704\ud574 \uc774\ub97c \uba85\uc2dc\ud558\ub294 \uc774\uc720\uc785\ub2c8\ub2e4.<\/p>\n\n    <h2 id=\"specifications\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">\ubb3c\ub9ac\ud654\ud559\uc801 \uc0ac\uc591 (COA \ubca4\uce58\ub9c8\ud06c)<\/h2>\n    <p style=\"margin-bottom: 15px;\">\ud45c\uc900\ud654\ub418\uc9c0 \uc54a\uc740 \uc2dd\ubb3c \ucd94\ucd9c\ubb3c\uc5d0 \uc758\uc874\ud558\ub294 \uac83\uc740 \uc81c\ud615\uc758 \uc77c\uad00\uc131\uc744 \ud574\uce69\ub2c8\ub2e4. \uc815\ubc00\ud568\uc740 \ubd84\uc11d \uac80\uc99d\uc744 \uc694\uad6c\ud569\ub2c8\ub2e4. \uc6d0\ub8cc COA\ub97c \uc774\ub7ec\ud55c \uae30\uc900 \uc9c0\ud45c\uc640 \ube44\uad50\ud558\uc2ed\uc2dc\uc624.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Parameter<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">\uaddc\uaca9 \ud45c\uc900<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">\uc2dc\ud5d8 \ubc29\ubc95 \/ \ube44\uace0<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\ud65c\uc131 \ub9c8\ucee4<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #047857; font-weight: bold;\">\ub9ac\ucf54\uce7c\ucf58 A \u2265 20.0%<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">HPLC<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\ubaa8\uc2b5<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\ub178\ub780\uc0c9\uc5d0\uc11c \uac08\uc0c9\uc744 \ub764 \ub178\ub780\uc0c9 \ubd84\ub9d0<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\uc721\uc548. \uac15\ub82c\ud55c \ub178\ub780\uc0c9\uc740 \uce7c\ucf58\uc758 \uace0\uc720\ud55c \ud2b9\uc9d5\uc785\ub2c8\ub2e4.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\uc6a9\ud574\ub3c4<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\ubb3c\uc5d0 \ubd88\uc6a9\uc131. \ud504\ub85c\ud544\ub80c \uae00\ub9ac\ucf5c, \uc5d0\ud0c4\uc62c\uc5d0 \uc6a9\ud574\ub428.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\ubb3c\ub9ac\uc801 \uac80\uc99d.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\uac74\uc870 \uac10\ub7c9<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\u2264 5.0%<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">105\u00b0C\uc5d0\uc11c 2\uc2dc\uac04.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\ud68c\ubd84 \ud568\ub7c9<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\u2264 2.0%<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">800\u00b0C\uc5d0\uc11c \uac15\uc5f4.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\uc911\uae08\uc18d<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #b91c1c; font-weight: bold;\">\u2264 10 ppm \ucd1d\ub7c9. (Pb \u2264 2ppm, As \u2264 1ppm)<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">ICP-MS. \uc5c4\uaca9\ud55c FDA\/EU \uaddc\uc815 \uc900\uc218\ub97c \uc704\ud574 \ud544\uc218\uc801\uc785\ub2c8\ub2e4.<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"efficacy\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">\uc2dc\ud5d8\uad00 \ub0b4 \ud6a8\ub2a5: \uac1d\uad00\uc801\uc778 \ub370\uc774\ud130<\/h2>\n    <p style=\"margin-bottom: 15px;\">\ub9c8\ucf00\ud305 \uc8fc\uc7a5\uc740 \uc190\uc0c1\ub41c \uc7a5\ubcbd\uc744 \ubcf5\uad6c\ud558\uc9c0 \ubabb\ud569\ub2c8\ub2e4. \uc2e4\uc81c \ub370\uc774\ud130\uac00 \ubcf5\uad6c\ud569\ub2c8\ub2e4. \uc2e4\ud5d8\uc2e4 \uc131\ub2a5\uc744 \uc0b4\ud3b4\ubcf4\uaca0\uc2b5\ub2c8\ub2e4.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">\ud0c0\uac9f \/ \uacbd\ub85c<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">\ud6a8\ub2a5 \uac12<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">\uc784\uc0c1\uc801 \uad00\ub828\uc131<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>PGE2 \uc0dd\uc131<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">IC50 \u2248 1.8 \u03bcM<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">UV \uc720\ubc1c \ud64d\uc870\ub97c \ud604\uc800\ud788 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \uae09\uc131 \ubaa8\uc138\ud608\uad00 \ud655\uc7a5 \uc644\ud654.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\ud050\ud2f0\ubc15\ud14c\ub9ac\uc6c0 \uc544\ud06c\ub124\uc2a4<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">MIC 5.0 \u2013 15.0 \u03bcg\/mL<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\uc9c1\uc811\uc801\uc778 \uc0b4\uade0 \ud6a8\uacfc. \uc0b0\uc131 \uac01\uc9c8 \uc81c\uac70 \uc5c6\uc774 \uc5fc\uc99d\uc131 \uc5ec\ub4dc\ub984 \ud0c0\uac9f\ud305.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Nrf2 \ud65c\uc131\ud654<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">HO-1 \uc720\ub3c4 5-10 \u03bcM<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\uc138\ud3ec \ub0b4 \ud56d\uc0b0\ud654 \ubc29\uc5b4\ub825 \uc99d\uc9c4. 2\ucc28 \uc9c0\uc9c8 \uacfc\uc0b0\ud654\ub85c\ubd80\ud130 \ubcf4\ud638.<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"synergies\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">\uc81c\ud615 \uc2dc\ub108\uc9c0: PIE \ubc0f \ud64d\uc870 \ud0c0\uac9f\ud305<\/h2>\n    <p style=\"margin-bottom: 15px;\">\ud65c\uc131 \uc131\ubd84\uc740 \ub9e4\ud2b8\ub9ad\uc2a4 \ub0b4\uc5d0\uc11c \ud611\ub825\ud574\uc57c \ud569\ub2c8\ub2e4. \ud604\uc7ac \uc784\uc0c1 \ud2b8\ub80c\ub4dc\ub294 \ube44\ud30c\uad34\uc801 \uac1c\uc785\uc744 \uc6b0\uc120\uc2dc\ud569\ub2c8\ub2e4. Glycyrrhiza Inflata\ub97c \uc804\ub7b5\uc801\uc73c\ub85c \ud398\uc5b4\ub9c1\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">\uc2dc\ub108\uc9c0 \ud30c\ud2b8\ub108<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">\uc0c1\ud638 \uc791\uc6a9 \uba54\ucee4\ub2c8\uc998<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">\ud0c0\uac9f \uc801\uc751\uc99d<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Tranexamic Acid<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\ud2b8\ub77c\ub125\uc0bc\uc0b0\uc740 \ud50c\ub77c\uc2a4\ubbf8\ub178\uac90\uc744 \ucc28\ub2e8\ud569\ub2c8\ub2e4. \ub9ac\ucf54\uce7c\ucf58 A\ub294 COX-2\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4. \ud568\uaed8 \ud608\uad00 \uc2e0\uc0dd\uc744 \ucc28\ub2e8\ud569\ub2c8\ub2e4.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #b91c1c; font-weight: bold;\">\uc5fc\uc99d \ud6c4 \ud64d\uc870 (PIE)<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\ubcd1\ud480 \ucd94\ucd9c\ubb3c (\ub9c8\ub370\uce74\uc18c\uc0ac\uc774\ub4dc)<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\ub9c8\ub370\uce74\uc18c\uc0ac\uc774\ub4dc\ub294 \ucf5c\ub77c\uac90 III \ud569\uc131\uc744 \uac00\uc18d\ud654\ud569\ub2c8\ub2e4. \ub9ac\ucf54\uce7c\ucf58 A\ub294 \uc5fc\uc99d \uc2e0\ud638\uac00 \ud68c\ubcf5\uc744 \uc9c0\uc5f0\uc2dc\ud0a4\ub294 \uac83\uc744 \ubc29\uc9c0\ud569\ub2c8\ub2e4.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\uc2dc\uc220 \ud6c4 \ud68c\ubcf5<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>\uadc0\ub9ac \ubca0\ud0c0\uae00\ub8e8\uce78<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\ubca0\ud0c0-\uae00\ub8e8\uce78\uc740 \uace0\ubd84\uc790\ub7c9 \ud45c\uba74 \ubcf4\ud638\ub9c9\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub9ac\ucf54\uce7c\ucf58 A\ub294 \uae4a\uc740 \uc5fc\uc99d \uc5f0\uc1c4 \ubc18\uc751\uc744 \ucc28\ub2e8\ud569\ub2c8\ub2e4.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\ub9cc\uc131 \ud53c\ubd80\uc5fc<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"solubility\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">\uc6a9\ud574\ub3c4 \ud30c\ub77c\ubbf8\ud130 \ubc0f \uc2e4\ud5d8\uc2e4 \uacf5\uc815<\/h2>\n    <p style=\"margin-bottom: 15px;\">\ub9ac\ucf54\uce7c\ucf58 A\ub294 \ubb3c\uc744 \uc2eb\uc5b4\ud569\ub2c8\ub2e4. \ub9e4\uc6b0 \uc18c\uc218\uc131\uc785\ub2c8\ub2e4. \uc218\uc131 \uc0c1\uc5d0 \uc9c1\uc811 \ucca8\uac00\ud558\uba74? \uc989\uc2dc \uce68\uc804\ub429\ub2c8\ub2e4. \uc0dd\uccb4 \uc774\uc6a9\ub960\uc740 0\uc73c\ub85c \ub5a8\uc5b4\uc9d1\ub2c8\ub2e4.<\/p>\n    <ul style=\"padding-left: 20px; margin-bottom: 20px;\">\n        <li style=\"margin-bottom: 10px;\"><strong>Solvent Selection:<\/strong> \ubd84\ub9d0\uc744 \uc0ac\uc804 \ubd84\uc0b0\ud558\uc2ed\uc2dc\uc624. \ud504\ub85c\ud544\ub80c \uae00\ub9ac\ucf5c, \ubd80\ud2f8\ub80c \uae00\ub9ac\ucf5c \ub610\ub294 PEG-400\uc744 \uc0ac\uc6a9\ud558\uc2ed\uc2dc\uc624. \ud22c\uba85\ud55c \uc138\ub7fc\uc774 \ud544\uc694\ud558\uc2ed\ub2c8\uae4c? \uc5d0\ud1a1\uc2dc\ub514\uae00\ub9ac\ucf5c (\ud2b8\ub79c\uc2a4\ucef7\uc62c)\uacfc \uacc4\uba74\ud65c\uc131\uc81c (\ud3f4\ub9ac\uc18c\ub974\ubca0\uc774\ud2b8 20)\ub97c \ud568\uaed8 \uc0ac\uc6a9\ud558\ub294 \uac83\uc774 \ud544\uc218\uc801\uc785\ub2c8\ub2e4.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>\uc628\ub3c4 \ud504\ub85c\ud1a0\ucf5c:<\/strong> \uae00\ub9ac\ucf5c \uc0c1\uc744 45\u00b0C \u2013 55\u00b0C\ub85c \uac00\uc5f4\ud558\uc2ed\uc2dc\uc624. \uc644\uc804\ud55c \uc6a9\ud574\ub97c \ubcf4\uc7a5\ud558\uc2ed\uc2dc\uc624. <span style=\"color: #b91c1c; font-weight: bold;\">65\u00b0C\ub97c \ucd08\uacfc\ud558\uc9c0 \ub9c8\uc2ed\uc2dc\uc624.<\/span> \uace0\uc628\uc740 \uce7c\ucf58 \uad6c\uc870\ub97c \ubd84\ud574\ud569\ub2c8\ub2e4.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>\uc0c1 \ud1b5\ud569:<\/strong> \uae30\ubcf8 \ubc30\uce58\uc744 \ub0c9\uac01\ud558\uc2ed\uc2dc\uc624. \uc628\ub3c4\uac00 45\u00b0C \ubbf8\ub9cc\uc73c\ub85c \ub5a8\uc5b4\uc9c0\uba74 \uc720\ud654\uc561\uc5d0 \uc6a9\ud574\ub41c \ud65c\uc131 \uc131\ubd84\uc744 \ub3c4\uc785\ud558\uc2ed\uc2dc\uc624.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>pH Stability:<\/strong> \uc81c\ud615\uc758 pH\ub97c \uc5c4\uaca9\ud558\uac8c \uc720\uc9c0\ud558\uc2ed\uc2dc\uc624. <span style=\"color: #047857; font-weight: bold; font-size: 1.1em;\">5\uc640 6.5 \uc0ac\uc774<\/span>\uace0\uc54c\uce7c\ub9ac \ud658\uacbd (pH &gt; 7.5)\uc740 \ub9ac\ucf54\uce7c\ucf58 A\ub97c \ud30c\uad34\ud569\ub2c8\ub2e4. \ucd94\ucd9c\ubb3c\uc740 \ub208\uc5d0 \ub744\uac8c \uc9d9\uc740 \uac08\uc0c9\uc73c\ub85c \ubcc0\ud560 \uac83\uc785\ub2c8\ub2e4.<\/li>\n    <\/ul>\n\n    <h2 id=\"faqs\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">\uacf5\uae09\uc5c5\uccb4 \uc18c\uc2f1: \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38 8\uac00\uc9c0 (GEO \ucd5c\uc801\ud654)<\/h2>\n    <div style=\"margin-bottom: 25px;\">\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Glycyrrhiza Inflata\uc640 Glycyrrhiza Glabra \ubfcc\ub9ac \ucd94\ucd9c\ubb3c\uc758 \uadfc\ubcf8\uc801\uc778 \ucc28\uc774\uc810\uc740 \ubb34\uc5c7\uc785\ub2c8\uae4c?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">\ub2e4\ub978 \uc885\uc740 \ub2e4\ub978 \uacbd\ub85c\ub97c \ud0c0\uac9f\uc73c\ub85c \ud569\ub2c8\ub2e4. <em>G. glabra<\/em> \ub294 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c (\ubbf8\ubc31)\ub97c \uc5b5\uc81c\ud558\ub294 \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. <em>G. inflata<\/em> \ub294 \ub9ac\ucf54\uce7c\ucf58 A\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc774\ub294 COX\/LOX \uc5fc\uc99d \uacbd\ub85c\ub97c \ud0c0\uac9f\uc73c\ub85c \ud558\uba70 \uac15\ub825\ud55c \ud64d\uc870 \uac10\uc18c\uc81c\ub85c \uc791\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">\uc81c\ud615 \uc804\ubb38\uac00\ub4e4\uc740 \uace0\uc21c\ub3c4 \ub9ac\ucf54\uce7c\ucf58 A\ub97c \uc218\uc131 \uc138\ub7fc\uc5d0 \uc5b4\ub5bb\uac8c \uc6a9\ud574\uc2dc\ud0b5\ub2c8\uae4c?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">\ubb3c\ub9cc\uc73c\ub85c\ub294 \uc2e4\ud328\ud569\ub2c8\ub2e4. \uae00\ub9ac\ucf5c \uc2dc\uc2a4\ud15c (\ubd80\ud2f8\ub80c \uae00\ub9ac\ucf5c \ub4f1)\uc5d0 \ubd84\ub9d0\uc744 \uc0ac\uc804 \uc6a9\ud574\ud574\uc57c \ud569\ub2c8\ub2e4. \uc644\uc804\ud788 \ud22c\uba85\ud55c \uc218\uc131 \uc138\ub7fc\uc758 \uacbd\uc6b0, \uc218\uc131 \ud1b5\ud569 \uc804\uc5d0 \uacc4\uba74\ud65c\uc131\uc81c (PEG-40 \uc218\uc18c\ud654 \ud53c\ub9c8\uc790\uc720)\uc640 \uace0\uc804\ub2e8 \ud63c\ud569\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">\ub9ac\ube0c\uc628 \uc2a4\ud0a8\ucf00\uc5b4 \uc81c\ud488\uc758 \ucd5c\uc801 \uc0ac\uc6a9\ub7c9 \ubc94\uc704\ub294 \uc5bc\ub9c8\uc785\ub2c8\uae4c?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">\ub9ac\ube0c\uc628 \uc720\ud654\uc561\uc758 \uacbd\uc6b0 <span style=\"color: #047857; font-weight: bold;\">05%\uc640 0.5% \uc0ac\uc774<\/span> \ub97c \uc720\uc9c0\ud558\uc2ed\uc2dc\uc624. \uc77c\uc77c \uc7a5\ubcbd \uc720\uc9c0\ub294 \uc57d 0.1%\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uae09\uc131 \ud64d\uc870 \uc644\ud654 \ub610\ub294 PIE \uce58\ub8cc\uc5d0\ub294 0.3%\uc5d0\uc11c 0.5%\uac00 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Glycyrrhiza Inflata \ucd94\ucd9c\ubb3c\uc740 \uad11\ub3c5\uc131 \uc704\ud5d8\uc774 \uc788\uc2b5\ub2c8\uae4c?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">\uc544\ub2c8\uc694. \uc2e4\ud5d8\uc2e4 \ud14c\uc2a4\ud2b8\uc5d0\uc11c \uad11\ub3c5\uc131\uc774 \uc5c6\uc74c\uc744 \ud655\uc778\ud588\uc2b5\ub2c8\ub2e4. \ub3d9\ub8cc \uac80\ud1a0 \ub370\uc774\ud130\ub294 \uc2e4\uc81c\ub85c Nrf2\ub97c \ud65c\uc131\ud654\ud55c\ub2e4\uace0 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc774\ub294 UV \uc720\ubc1c \ud64d\uc870\ub97c \uc9c0\uc5f0\uc2dc\ud0a4\uace0 UV \uc720\ubc1c \uc138\ud3ec \uc0ac\uba78\uc744 \ubc29\uc9c0\ud569\ub2c8\ub2e4.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">\uc774 \ucd94\ucd9c\ubb3c\uc740 \uc77c\ubc18\uc801\uc778 \uc0b0\uacfc \ube44\uad50\ud558\uc5ec Cutibacterium acnes\uc5d0 \ub300\ud574 \uc5b4\ub5bb\uac8c \uc791\uc6a9\ud569\ub2c8\uae4c?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">\uc0b4\ub9ac\uc2e4\uc0b0\uc740 \uc8fd\uc740 \ud53c\ubd80 \uc138\ud3ec\ub97c \ubd84\ub9ac\ud558\uc5ec \ubaa8\uacf5\uc744 \ub9c9\uc2b5\ub2c8\ub2e4. Glycyrrhiza Inflata\ub294 \ubc15\ud14c\ub9ac\uc544\ub97c \uc9c1\uc811 \uacf5\uaca9\ud569\ub2c8\ub2e4. 5.0 \u2013 15.0 \u03bcg\/mL\uc758 MIC\ub97c \ubcf4\uc720\ud569\ub2c8\ub2e4. <em>C. acnes<\/em>AHA\/BHA\ub85c \uc778\ud55c \ubc97\uaca8\uc9d0 \uc5c6\uc774 \ud56d\uade0 \uc791\uc6a9\uc744 \ub2ec\uc131\ud569\ub2c8\ub2e4.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">\ud2b9\uc815 \uc81c\ud615\uc5d0\uc11c \ucd94\ucd9c\ubb3c\uc758 \uc0c9\uc774 \ubcc0\ud558\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc785\ub2c8\uae4c?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">\uc54c\uce7c\ub9ac\uc131\uc740 \uce7c\ucf58\uc744 \ud30c\uad34\ud569\ub2c8\ub2e4. \uc81c\ud615\uc758 pH\uac00 7.0 \uc774\uc0c1\uc73c\ub85c \uc62c\ub77c\uac00\uba74 \ucd94\ucd9c\ubb3c\uc740 \uace0\ub9ac \uc5f4\ub9bc\uc744 \uacaa\uc2b5\ub2c8\ub2e4. \uc801\uac08\uc0c9\uc73c\ub85c \ubcc0\ud569\ub2c8\ub2e4. \ud6a8\ub2a5\uc740 \uc0ac\ub77c\uc9d1\ub2c8\ub2e4. pH \uc644\ucda9\uc561\uc744 4.5\uc640 6.5 \uc0ac\uc774\ub85c \uace0\uc815\ud558\uc2ed\uc2dc\uc624.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">\uac10\ucd08 \uc720\ub798 \uc6d0\ub8cc\uc5d0 \uc911\uae08\uc18d \uaddc\uc815 \uc900\uc218 \ubb38\uc81c\uac00 \uc788\uc2b5\ub2c8\uae4c?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">\uc608. \uac10\ucd08 \ubfcc\ub9ac\ub294 \ud1a0\uc591\uc5d0\uc11c \uc911\uae08\uc18d\uc744 \uc801\uadf9\uc801\uc73c\ub85c \uc0dd\ubb3c \ucd95\uc801\ud569\ub2c8\ub2e4. \uc800\ud488\uc9c8 \ucd94\ucd9c\ubb3c\uc740 \uc548\uc804 \ud14c\uc2a4\ud2b8\ub97c \ud1b5\uacfc\ud558\uc9c0 \ubabb\ud569\ub2c8\ub2e4. \uc5c4\uaca9\ud55c ICP-MS \ud14c\uc2a4\ud2b8\ub97c \ud1b5\ud574 \ucd1d \uc911\uae08\uc18d\uc774 \u2264 10 ppm\uc784\uc744 \uc99d\uba85\ud558\ub294 COA\ub97c \uc694\uad6c\ud558\uc2ed\uc2dc\uc624.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">\uc800 pH\uc758 L-\uc544\uc2a4\ucf54\ub974\ube0c\uc0b0(\ube44\ud0c0\ubbfc C)\uacfc \uc9c1\uc811 \ubc30\ud569\uc774 \uac00\ub2a5\ud55c\uac00\uc694?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">\uace0\uae09 \ubc30\ud569 \uae30\uc220\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \ub9ac\ucf54\uce7c\ucf58 A\uc758 \ud654\ud559 \uad6c\uc870\ub294 \ub0ae\uc740 pH\uc5d0\uc11c\ub3c4 \uc720\uc9c0\ub418\uc9c0\ub9cc, 15% \ube44\ud0c0\ubbfc C \uc138\ub7fc(pH 3.0 \u2013 3.5)\uc758 \ub192\uc740 \uc0b0\ub3c4\ub294 \uc6a9\ud574\ub3c4\ub97c \ud604\uc800\ud788 \ub0ae\ucda5\ub2c8\ub2e4. \uc5d0\ud1a1\uc2dc\ub514\uae00\ub9ac\ucf5c\uacfc \uac19\uc740 \uac15\ub825\ud55c \uc6a9\ub9e4 \uc9c0\uc6d0 \uc5c6\uc774\ub294 \ud65c\uc131 \uc131\ubd84\uc774 \uacb0\uc815\ud654\ub418\uc5b4 \uc138\ub7fc\uc5d0\uc11c \uce68\uc804\ub429\ub2c8\ub2e4.<\/p>\n    <\/div>\n\n    <h2 id=\"references\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px; border-top: 1px solid #e2e8f0; padding-top: 20px;\">\uad8c\uc704 \uc788\ub294 \ucc38\uace0 \ubb38\ud5cc<\/h2>\n    <ol style=\"padding-left: 20px; font-size: 14px; color: #475569;\">\n        <li style=\"margin-bottom: 8px;\">Kolbe, L. \ub4f1. (2006). \u201cLicochalcone A\uc758 \ud56d\uc5fc\uc99d \ud6a8\ub2a5: \uc784\uc0c1 \ud6a8\ub2a5\uacfc \uc2dc\ud5d8\uad00 \ub0b4 \ud6a8\uacfc\uc758 \uc0c1\uad00\uad00\uacc4.\u201d <em>Archives of Dermatological Research<\/em>, 298(1), 23-30.<\/li>\n        <li style=\"margin-bottom: 8px;\">Shibata, S. (2000). \u201c\uc218\ucc9c \ub144\uac04\uc758 \uc57d\ubb3c: \uac10\ucd08\uc758 \uc57d\uc6a9 \uc2dd\ubb3c\ud559, \ud654\ud559 \ubc0f \uc57d\ub9ac\ud559.\u201d <em>Yakugaku Zasshi<\/em>, 120(10), 849-862.<\/li>\n        <li style=\"margin-bottom: 8px;\">Yin, Z. \ub4f1. (2020). \u201cLicochalcone A\ub294 NF-\u03baB \ubc0f MAPK \uacbd\ub85c \uc5b5\uc81c\ub97c \ud1b5\ud574 \uc5fc\uc99d \ubc18\uc751\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.\u201d <em>International Journal of Molecular Medicine<\/em>, 45(4), 1187-1196.<\/li>\n        <li style=\"margin-bottom: 8px;\">Wu, L. \ub4f1. (2015). \u201cLicochalcone A\ub294 Nrf2 \ud56d\uc0b0\ud654 \ubc18\uc751 \uc694\uc18c \uc2e0\ud638\ub97c \ud65c\uc131\ud654\ud569\ub2c8\ub2e4\u2026\u201d <em>European Journal of Pharmacology<\/em>, 761, 33-41.<\/li>\n    <\/ol>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\ubaa9\ucc28 1. \ub9ac\ucf54\uce7c\ucf58 A\uc758 \ucc28\ubcc4\uc810: Nrf2 \ubc0f COX\/LOX 2. \ubb3c\ub9ac\ud654\ud559\uc801 \uc0ac\uc591 (COA \ubca4\uce58\ub9c8\ud06c) 3. \uc2dc\ud5d8\uad00 \ub0b4 \ud6a8\ub2a5: \uac1d\uad00\uc801\uc778 \uc218\uce58 4. \uc81c\ud615 \uc2dc\ub108\uc9c0:\u2026<\/p>","protected":false},"author":1,"featured_media":14737,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[357],"tags":[],"class_list":["post-15514","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-product-updates"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Formulating Licochalcone A: Glycyrrhiza Inflata Extract - Natural huatai<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.natural-huatai.com\/ko\/formulating-licochalcone-a-glycyrrhiza-inflata-extract\/\" \/>\n<meta property=\"og:locale\" content=\"ko_KR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Formulating Licochalcone A: Glycyrrhiza Inflata Extract\" \/>\n<meta property=\"og:description\" content=\"Table of Contents 1. The Licochalcone A Distinction: Nrf2 and COX\/LOX 2. Physicochemical Specifications (COA Benchmarks) 3. In-Vitro Efficacy: The Hard Numbers 4. 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