{"id":13718,"date":"2026-03-17T04:12:22","date_gmt":"2026-03-17T04:12:22","guid":{"rendered":"https:\/\/huataibio.com\/?post_type=product&#038;p=13718"},"modified":"2026-03-17T04:12:26","modified_gmt":"2026-03-17T04:12:26","slug":"phloretin","status":"publish","type":"product","link":"https:\/\/www.natural-huatai.com\/fr\/products\/phloretin\/","title":{"rendered":"Phloretin"},"content":{"rendered":"<blockquote><p><b data-path-to-node=\"6\" data-index-in-node=\"0\">Maximize your formulation\u2019s efficacy with our 98% high-purity Phloretin, a natural polyphenolic antioxidant that not only neutralizes free radicals but also acts as a powerful penetration enhancer for other active ingredients.<\/b> <b data-path-to-node=\"6\" data-index-in-node=\"227\">As a specialized manufacturer, Shaanxi Huatai Bio provides consistent bulk supply of premium white-to-off-white Phloretin powder, backed by COSMOS certification and full technical dossiers (COA\/MSDS\/TDS) to ensure global regulatory compliance.<\/b><\/p><\/blockquote>\n<h3>1. Product Overview &amp; Market Relevance<\/h3>\n<p data-path-to-node=\"9\">Phloretin is a high-performance bioactive compound primarily extracted from the root bark and fruit peel of apples. It is celebrated in the luxury skincare market for its triple-action benefits: antioxidant, anti-inflammatory, and skin brightening.<\/p>\n<ul data-path-to-node=\"10\">\n<li>\n<p data-path-to-node=\"10,0,0\"><b data-path-to-node=\"10,0,0\" data-index-in-node=\"0\">Superior Bioactivity:<\/b> Effectively inhibits the activity of melanocytes and prevents sebum overproduction, making it ideal for brightening and anti-acne formulations.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"10,1,0\"><b data-path-to-node=\"10,1,0\" data-index-in-node=\"0\">Advanced Penetration:<\/b> Unique molecular structure that helps improve the transdermal delivery of synergistic actives like Vitamin C and Ferulic Acid.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"10,2,0\"><b data-path-to-node=\"10,2,0\" data-index-in-node=\"0\">Factory-Direct Quality:<\/b> We offer an ultra-refined 98% purity grade with strict control over heavy metals and impurities, ensuring a stable and clean profile for your final products.<\/p>\n<\/li>\n<\/ul>\n<h3>2. Technical Highlights and Critical Parameters<\/h3>\n<h4>2.1 Mechanism of Action (MoA)<\/h4>\n<ul>\n<li><b>Skin Whitening:<\/b> Inhibits tyrosinase activity. Its inhibiting tyrosinase ability is reported to be better than arbutin and kojic acid. The blend of them can greatly improve the inhibition ratio of tyrosinase, about <span class=\"math-inline\" data-math=\"100\">100<\/span>\u00a0Percent.<\/li>\n<li><b>Anti-inflammatory and Immunosuppressive:<\/b> <span class=\"math-inline\" data-math=\"text{NO}\">NO<\/span>\u00a0production and phagocytosis rate of macrophages can be significantly reduced by phloretin.<\/li>\n<li><b>Antioxidant:<\/b> Phloretin can remove free radicals in the skin, effectively prevent aging, cell mutation, accelerate cell metabolism, reduce wrinkles, enhance the skin supporting structure, and immunity to <span class=\"math-inline\" data-math=\"text{UV}\">UV<\/span>\u00a0light.<\/li>\n<\/ul>\n<h4>2.2 Standard Technical Specifications<\/h4>\n<table>\n<thead>\n<tr>\n<td><strong>Parameter<\/strong><\/td>\n<td><strong>Specification (98 Percent Grade)<\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>Specification<\/b><\/td>\n<td><b>98 Percent<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Appearance<\/b><\/td>\n<td>White Powder<\/td>\n<\/tr>\n<tr>\n<td><b>Dosage (Recommendation)<\/b><\/td>\n<td><span class=\"math-inline\" data-math=\"5\">5<\/span> \u2030 \u2013 <span class=\"math-inline\" data-math=\"1\">1<\/span> <strong class=\"Yjhzub\" data-processed=\"true\">%<\/strong><\/td>\n<\/tr>\n<tr>\n<td><b>Solubility<\/b><\/td>\n<td>Soluble in ethanol, 1,3-butanediol etc. Not dissolved in water.<\/td>\n<\/tr>\n<tr>\n<td><b>Shelf Life<\/b><\/td>\n<td>24 months when properly stored<\/td>\n<\/tr>\n<tr>\n<td><b>Storage<\/b><\/td>\n<td>Store in tightly sealed and preferably full containers in cool, dry and ventilated area.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>3. Market Positioning and Core Advantages<\/h3>\n<ul>\n<li><b>Superior Whitening Potential:<\/b> Clinical data suggests <span class=\"math-inline\" data-math=\"3\">3<\/span> Percent Phloretin cream is superior to <span class=\"math-inline\" data-math=\"3\">3<\/span>\u00a0Percent Arbutin.<\/li>\n<li><b>Immunosuppressive Properties:<\/b> The results show that phloretin might be developed into a new immunosuppressive drug.<\/li>\n<li><b>Broad Protection:<\/b> Effective in <span class=\"math-inline\" data-math=\"text{UV}\">UV<\/span>-induced pigmentation prevention and comprehensive anti-aging benefits.<\/li>\n<\/ul>\n<h3>4. Formulation Guidelines<\/h3>\n<ul>\n<li><b>Integration Phase:<\/b> Must be dissolved in lipid-soluble solvents like ethanol or 1,3-butanediol, as it does not dissolve in water.<\/li>\n<li><b>Dosage:<\/b> Recommended dosage ranges from <span class=\"math-inline\" data-math=\"5\">5<\/span> Percent to <span class=\"math-inline\" data-math=\"1\">1<\/span>\u00a0Percent.<\/li>\n<li><b>Storage:<\/b> Store in a cool, dry, and ventilated area to maintain the <span class=\"math-inline\" data-math=\"24\">24<\/span>\u00a0month shelf life.<\/li>\n<\/ul>\n<h3>5. Quality Assurance and Regulatory Confidence<\/h3>\n<p>Our quality and safety credentials include:<\/p>\n<ul>\n<li><b>COSMOS (Natural and Organic Cosmetic Standard)<\/b><\/li>\n<li><b>ISO 9001 Quality Management System<\/b><\/li>\n<li><b>ISO 22000 Food Safety Management System<\/b><\/li>\n<li><b>HALAL Certification<\/b><\/li>\n<li><b>IQNET (The International Certification Network)<\/b><\/li>\n<li><b>Technical Dossier (Certificate of Analysis \u2013 COA, Technical Data Sheet \u2013 TDS, Material Safety Data Sheet \u2013 MSDS)<\/b><\/li>\n<\/ul>\n<h3>6. Typical Applications<\/h3>\n<ul>\n<li><b>Skinceuticals:<\/b> Phloretin <span class=\"math-inline\" data-math=\"text{CF}\">CF<\/span>.<\/li>\n<li><b>Cosmetic Skin Solutions:<\/b> Phloretin <span class=\"math-inline\" data-math=\"text{CF}\">CF<\/span> Serum Advanced Formula <span class=\"math-inline\" data-math=\"+\">+<\/span>.<\/li>\n<li><b>General Cosmetics:<\/b> Whitening creams, anti-acne treatments, anti-aging serums.<\/li>\n<\/ul>\n<h3>7. Scientific Evidence Summary<\/h3>\n<ul>\n<li><b>Skin Pigmentation:<\/b> The results suggest that <span class=\"math-inline\" data-math=\"3\">3<\/span>\u00a0Percent phloretin cream acts on skin pigmentation in the late phase after <span class=\"math-inline\" data-math=\"text{UV}\">UV<\/span>-induced and it is superior to <span class=\"math-inline\" data-math=\"3\">3<\/span>\u00a0Percent arbutin.<\/li>\n<li><b>Dose-Dependent Whitening:<\/b> The <span class=\"math-inline\" data-math=\"text{MI}\">MI<\/span>\u00a0value trend shows that <span class=\"math-inline\" data-math=\"0.5\">0.5<\/span> Percent, <span class=\"math-inline\" data-math=\"1\">1<\/span>\u00a0Percent, and <span class=\"math-inline\" data-math=\"3\">3<\/span>\u00a0Percent phloretin cream inhibit the formation of dark spots and the ability increase as the concentration increasing, there\u2019s a dose-dependent trend. The <span class=\"math-inline\" data-math=\"text{b}\">b<\/span> value figure also shows that the efficacy of <span class=\"math-inline\" data-math=\"3\">3<\/span>\u00a0Percent concentration phloretin cream is better than <span class=\"math-inline\" data-math=\"0.5\">0.5<\/span> Percent and <span class=\"math-inline\" data-math=\"1\">1<\/span>\u00a0Percent. The higher the concentration, the better the whitening effect.<\/li>\n<li><b>Immune Response:<\/b> The results showed that phloretin significantly inhibited the proliferation of <span class=\"math-inline\" data-math=\"text{T}\">T<\/span>\u00a0lymphocytes and the <span class=\"math-inline\" data-math=\"text{PI}\">PI<\/span> reduced from <span class=\"math-inline\" data-math=\"1.4 pm 0.13\">1.4 pm 0.13<\/span> to <span class=\"math-inline\" data-math=\"1.34 pm 0.16\">1.34 pm 0.16<\/span>, <span class=\"math-inline\" data-math=\"1.19 pm 0.12\">1.19 pm 0.12<\/span>\u00a0and <span class=\"math-inline\" data-math=\"1.07 pm 0.06\">1.07 pm 0.06<\/span>, respectively.<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-6235 aligncenter\" src=\"https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2025\/08\/3-1-2.png\" alt=\"\" width=\"595\" height=\"199\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-6234 aligncenter\" src=\"https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2025\/08\/3-2-2.png\" alt=\"\" width=\"548\" height=\"1082\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-6233 aligncenter\" src=\"https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2025\/08\/3-3-1.png\" alt=\"\" width=\"531\" height=\"345\" \/><\/p>\n<h3>8. Frequently Asked Questions<\/h3>\n<p>Q1: How does Phloretin\u2019s whitening ability compare to other popular agents?<\/p>\n<p>A: Phloretin\u2019s inhibiting tyrosinase ability is better than arbutin and kojic acid. Clinical results show that 3 Percent Phloretin cream is superior to 3 Percent Arbutin in pigmentation late phase after UV-induced.<\/p>\n<p>Q2: What is the recommended solvent for formulating Phloretin?<\/p>\n<p>A: It is soluble in ethanol and 1,3-butanediol but not in water.<\/p>\n<p>Q3: How effective is Phloretin as an immunosuppressive agent?<\/p>\n<p>A: Phloretin significantly reduced NO production and the phagocytosis rate of macrophages. It significantly inhibited the proliferation of T lymphocytes and the expression of CD69 and CD25P.<\/p>\n<p>&nbsp;<\/p>\n<p><b>Source our 98 Percent Phloretin for advanced skin whitening and anti-inflammatory formulations.<\/b><\/p>\n<blockquote><p><b>\ud83d\udd12 Get Your Technical Dossier:<\/b> Access TDS, MSDS, COA, and Clinical Efficacy Reports.<\/p>\n<p><b>\ud83d\udd2c Apply for a Free Sample:<\/b> <b>Test the superior efficacy and purity of Phloretin today.<\/b><\/p>\n<p><b>\ud83d\udcde Get a Customized Quote:<\/b> Discuss bulk orders and high-purity specifications.<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<p><b>A Dihydrochalcone Compound with Superior Whitening and Anti-inflammatory Efficacy<\/b><\/p>\n<p>Phloretin is a dihydrochalcone compound and a type of natural phenol. Extracted from peels or root barks of apples, it is a new natural skin whitening agent. Phloretin helps anti-acne as it weakens estrogen activity. This ingredient is provided at a high purity of 98 Percent as a white powder, making it suitable for advanced cosmetic and dermatological applications.<\/p>","protected":false},"featured_media":13191,"template":"","meta":[],"etheme_brands":[],"product_cat":[22],"product_tag":[],"class_list":{"0":"post-13718","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-brightening","8":"first","9":"instock","10":"shipping-taxable","11":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Phloretin Suppliers &amp; Wholesalers | Cosmetic Grade - HuaTai<\/title>\n<meta name=\"description\" content=\"Reliable China Skincare Ingredients Source Factory &amp; Supplier of high-purity Phloretin. 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