{"id":13534,"date":"2026-03-17T04:11:31","date_gmt":"2026-03-17T04:11:31","guid":{"rendered":"https:\/\/huataibio.com\/?post_type=product&#038;p=13534"},"modified":"2026-03-23T07:09:21","modified_gmt":"2026-03-23T07:09:21","slug":"licochalcone-a","status":"publish","type":"product","link":"https:\/\/www.natural-huatai.com\/fr\/products\/licochalcone-a\/","title":{"rendered":"Licochalcone A"},"content":{"rendered":"<blockquote><p>Shaanxi Huatai Bio-Fine Chemical is a specialized manufacturer of Licochalcone A (CAS No. 58749-22-7), a potent flavonoid isolated from the root of Glycyrrhiza inflata (Licorice).<\/p>\n<p>We provide premium grade Licochalcone A ranging from 70% to 95% purity, which appears as a characteristic brownish yellow powder. Recognized for its exceptional anti-inflammatory and bacteria-inhibiting properties, it is a gold-standard ingredient for formulating products targeting sensitive skin, rosacea, and acne. Unlike generic extracts, our Licochalcone A ensures low solvent residue and high stability, making it ideal for high-end dermo-cosmetic applications.<\/p><\/blockquote>\n<h3>1. Product Overview &amp; Key Specifications<\/h3>\n<p>Licochalcone A is a chalcone-type compound found in the Licorice plant. Our Licochalcone A is predominantly extracted from the Licorice root and stem, as these parts are richer in Licochalcone A than leaves and seeds. Due to its complex structure, it is a high-cost, high-value ingredient. It is an effective solution for reducing the occurrence of inflammatory skin diseases.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-5821\" src=\"https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2025\/10\/Licochalcone-A.jpg\" alt=\"Licochalcone A\" width=\"500\" height=\"300\" \/><\/p>\n<h3>2. Technical Highlights &amp; Critical Parameters<\/h3>\n<p>We provide the hard data R&amp;D teams need to ensure seamless formulation and superior performance.<\/p>\n<h4>2.1 Licochalcone A Core Efficacy<\/h4>\n<ul>\n<li><b>Anti-Aging &amp; ROS Reduction:<\/b> Licochalcone A reduces <b>ROS (Reactive Oxygen Species) levels<\/b> and inhibits telomere shortening, which are primary factors in cellular senescence.<\/li>\n<li><b>Anti-Inflammatory Action:<\/b> LA can inhibit the synthesis of <span class=\"math-inline\" data-math=\"text{NO}\">NO<\/span> (Nitric Oxide) and the expression of iNOS (inducible Nitric Oxide Synthase) and <span class=\"math-inline\" data-math=\"text{COX}-2\">COX-2<\/span>\u00a0(Cyclooxygenase-2). This prevents the release of pro-inflammatory factors and reduces the frequency of inflammatory skin issues.<\/li>\n<li><b>Broad Application:<\/b> Licochalcone A is suitable for combating various skin inflammations, such as pediatric atopic dermatitis and photo-inflammation caused by UV radiation.<\/li>\n<\/ul>\n<h4>2.2 Customizable Grade Options<\/h4>\n<table>\n<thead>\n<tr>\n<td><strong>Content<\/strong><\/td>\n<td><strong>Physical Form<\/strong><\/td>\n<td><strong>Solubility<\/strong><\/td>\n<td><strong>Recommended Use Level<\/strong><\/td>\n<td><strong>Shelf Life<\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>20%<\/b><\/td>\n<td>Brownish Yellow Powder<\/td>\n<td>Alcohol Soluble<\/td>\n<td><b>0.1% &#8211; 2%<\/b><\/td>\n<td>24 Months<\/td>\n<\/tr>\n<tr>\n<td><b>70%<\/b><\/td>\n<td>Brownish Yellow Powder<\/td>\n<td>Alcohol Soluble<\/td>\n<td><b>0.1% &#8211; 2%<\/b><\/td>\n<td>24 Months<\/td>\n<\/tr>\n<tr>\n<td><b>95%<\/b><\/td>\n<td>Brownish Yellow Powder<\/td>\n<td>Alcohol Soluble<\/td>\n<td><b>0.1% &#8211; 2%<\/b><\/td>\n<td>24 Months<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b>Storage Condition:<\/b> Avoid light, ventilation, dry, in a sealed space.<\/p>\n<h3>3. Mechanism of Action (MoA)<\/h3>\n<p>LA primarily works by <b>downregulating inflammatory pathways<\/b> and <b>combating oxidative stress<\/b> at the cellular level. Its mechanism includes:<\/p>\n<ol start=\"1\">\n<li><b>Reducing <span class=\"math-inline\" data-math=\"text{ROS}\">ROS<\/span>\u00a0Levels<\/b> that lead to cellular senescence.<\/li>\n<li><b>Inhibiting the release of pro-inflammatory factors<\/b> to prevent skin inflammation.<\/li>\n<li><b>Inhibiting Tyrosinase<\/b> activity while showing clear inhibition against <b>Staphylococcus aureus<\/b>.<\/li>\n<\/ol>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-5875 alignright\" src=\"https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2025\/10\/Licochalcone-A-1-924x1024.jpg\" alt=\"Licochalcone A\" width=\"470\" height=\"521\" \/><\/p>\n<h3>4. Core Advantages &amp; Market USPs<\/h3>\n<h4>4.1 Competitive Edge for Your Brand<\/h4>\n<ul>\n<li><b>Multi-Functional Power:<\/b> Simultaneously delivers <b>Anti-Aging, Anti-Inflammatory, and Antibacterial<\/b> benefits.<\/li>\n<li><b>Targeted Anti-Aging:<\/b> Directly targets the root cause of aging by reducing <span class=\"math-inline\" data-math=\"text{ROS}\">ROS<\/span>\u00a0and inhibiting telomere shortening.<\/li>\n<li><b>High Purity (up to 95%):<\/b> Ensures potent efficacy for advanced formulations.<\/li>\n<li><b>Natural Anti-Inflammatory:<\/b> An excellent natural solution for sensitive, reactive, and acne-prone skin.<\/li>\n<\/ul>\n<h3>5. Formulation Guidelines<\/h3>\n<ul>\n<li><b>Recommended Use Level:<\/b> <span class=\"math-inline\" data-math=\"0.1% - 2%\">0.1% &#8211; 2%<\/span>\u00a0across all grades.<\/li>\n<li><b>Dissolution Advice:<\/b> As an alcohol-soluble powder, it should be pre-dissolved in the alcohol or oil phase of the formulation.<\/li>\n<li><b>High Purity Benefits:<\/b> The <span class=\"math-inline\" data-math=\"95%\">95%<\/span>\u00a0purity grade is ideal for highly targeted serums and spot treatments.<\/li>\n<\/ul>\n<h3>6. Quality Assurance &amp; Regulatory Confidence<\/h3>\n<p>We are committed to the highest standards of quality and regulatory compliance.<\/p>\n<h4>6.1 Certificate Section<\/h4>\n<p>Our quality and safety credentials include:<\/p>\n<ul>\n<li><b>COSMOS (Natural and Organic Cosmetic Standard)<\/b><\/li>\n<li><b>ISO 9001 Quality Management System<\/b><\/li>\n<li><b>ISO 22000 Food Safety Management System<\/b><\/li>\n<li><b>HALAL Certification<\/b><\/li>\n<li><b>IQNET (The International Certification Network)<\/b><\/li>\n<li><b>Technical Dossier<\/b> (Certificate of Analysis \u2013 COA, Technical Data Sheet \u2013 TDS, Material Safety Data Sheet \u2013 MSDS)<\/li>\n<\/ul>\n<h3>7. Recommended Synergistic Combinations<\/h3>\n<ul>\n<li><b>Licochalcone A + <a href=\"https:\/\/www.natural-huatai.com\/fr\/product\/ceramide\/\">Ceramides<\/a>:<\/b> Combines anti-inflammatory repair with skin barrier restoration.<\/li>\n<li><b>Licochalcone A + <a href=\"https:\/\/www.natural-huatai.com\/fr\/product\/niacinamide\/\">Niacinamide<\/a>:<\/b> Synergistic in combating acne, redness, and inflammation.<\/li>\n<\/ul>\n<h3>8. Typical Applications &amp; Success Stories<\/h3>\n<ul>\n<li><b>Industry Validation:<\/b> Used in high-end derma-cosmetic brands targeting sensitive, acne, and redness-prone skin.<\/li>\n<li><b>Product Categories:<\/b> Anti-Aging Serums, Sensitive Skin Toners, Anti-Redness Creams, Post-Procedure Care.<\/li>\n<\/ul>\n<h3>9. Scientific Evidence &amp; Literature Support<\/h3>\n<p>Based on internal lab summaries, our Licochalcone A provides powerful cellular protection:<\/p>\n<h4>9.1 Research Abstracts<\/h4>\n<ul>\n<li><b>Anti-Aging and <span class=\"math-inline\" data-math=\"text{ROS}\">ROS<\/span>\u00a0Reduction:<\/b> High <span class=\"math-inline\" data-math=\"text{ROS}\">ROS<\/span> levels are a primary cause of cellular senescence. Compared to the control group, Licochalcone A<span class=\"math-inline\" data-math=\"text{LA}\">LA<\/span> at a concentration of 25 <span class=\"math-inline\" data-math=\"25 mu text{mol\/L}\">mol\/L<\/span> significantly reduced the <span class=\"math-inline\" data-math=\"text{ROS}\">ROS<\/span> level in <span class=\"math-inline\" data-math=\"text{hADSCs}\">hADSCs<\/span> (human adipose-derived stem cells) and suppressed telomere shortening (<span class=\"math-inline\" data-math=\"P &lt; 0.05\">P &lt; 0.05<\/span>). This indicates its protective role against aging.<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5924\" src=\"https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1-1024x609.png\" alt=\"\" width=\"555\" height=\"330\" srcset=\"https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1-1024x609.png 1024w, https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1-300x178.png 300w, https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1-768x457.png 768w, https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1-18x12.png 18w, https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1-600x357.png 600w, https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1-1x1.png 1w, https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1-10x6.png 10w, https:\/\/www.natural-huatai.com\/wp-content\/uploads\/2024\/10\/11-1.png 1191w\" sizes=\"auto, (max-width: 555px) 100vw, 555px\" \/><\/p>\n<ul>\n<li><b>Anti-Inflammatory Mechanism:<\/b> LA reduces the release of pro-inflammatory factors, which helps prevent skin inflammation.<\/li>\n<li><b>Dual Action:<\/b> LA demonstrates the function of inhibiting tyrosinase activity and exhibits a clear inhibitory effect on <b>Staphylococcus aureus<\/b>.<\/li>\n<\/ul>\n<h3>10. Stability and Safety Data Summary<\/h3>\n<ul>\n<li><b>Safety:<\/b> Derived from natural licorice, LA is generally well-tolerated and is used in sensitive skin products globally.<\/li>\n<li><b>Stability:<\/b> All powder grades (20%, 70%, 95%) guarantee a 24-month shelf life when stored under recommended conditions.<\/li>\n<\/ul>\n<h3>11. Frequently Asked Questions (FAQ)<\/h3>\n<p>Q1: What is the recommended solvent for dissolving Licochalcone A 95%?<\/p>\n<p>A: All grades of Licochalcone A are alcohol-soluble, making alcohol the primary recommended solvent for pre-dissolution.<\/p>\n<p>Q2: Is Licochalcone A suitable for sensitive skin formulations?<\/p>\n<p>A: Yes. Its primary function as an anti-inflammatory and soothing agent makes it highly suitable for sensitive, irritated, and redness-prone skin products.<\/p>\n<p>Q3: How does Licochalcone A combat aging?<\/p>\n<p>A: It works at the cellular level by reducing harmful ROS (free radicals) and suppressing the factors (P16ink4a) that drive cell senescence and telomere shortening.<\/p>\n<p>Q4: Does Licochalcone A offer preservative benefits?<\/p>\n<p>A: While its primary role is functional, it exhibits inhibitory effects against certain bacteria like Staphylococcus aureus, which contributes to overall formulation integrity.<\/p>\n<p>&nbsp;<\/p>\n<p><b>Source the Advanced Natural Chalcone for Next-Generation Anti-Aging Formulas.<\/b><\/p>\n<blockquote><p><b>\ud83d\udd12 Get Your Technical Dossier:<\/b> Access TDS, MSDS, COA and Safety Reports.<\/p>\n<p><b>\ud83d\udd2c Apply for a Free Sample:<\/b> Test the anti-inflammatory power of Licochalcone A today.<\/p>\n<p><b>\ud83d\udcde Get a Customized Quote:<\/b> Discuss bulk orders and high-purity specifications.<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<div class=\"message-box-content-wrapper-nDROih\">\n<div class=\"message-content message-box-content-lcvP3O receive-message-box-content-Ak2lgP samantha-message-box-content-h0ZP5s\" data-testid=\"message_content\">\n<div class=\"container-p2nY4f flow-markdown-body theme-samantha-D0_4Ug\" dir=\"ltr\" data-testid=\"message_text_content\" data-show-indicator=\"false\">\n<div class=\"auto-hide-last-sibling-br paragraph-u1TS5p paragraph-element br-paragraph-space\">\n<div class=\"write-content-HBP1KW\">\n<div class=\"scroll-view-VuVgIp write-content-inner-Tnxg93\">\n<div class=\"content-NfeEi5\">\n<div class=\"scrollable-xAHiOl\">\n<div class=\"children-wrapper-tALoJZ children-wrapper\">\n<div class=\"container-p2nY4f flow-markdown-body theme-samantha-D0_4Ug\" dir=\"ltr\" data-show-indicator=\"false\">\n<div class=\"auto-hide-last-sibling-br paragraph-u1TS5p paragraph-element\"><strong>The Powerful Anti-Inflammatory and Anti-Aging Chalcone<\/strong><\/div>\n<div><\/div>\n<\/div>\n<div class=\"container-p2nY4f flow-markdown-body theme-samantha-D0_4Ug\" dir=\"ltr\" data-show-indicator=\"false\">\n<div>A highly valuable compound extracted from the Licorice plant, Licochalcone A (LA) is a powerful multifunctional ingredient known for reducing ROS levels, inhibiting inflammation, and offering antibacterial effects against organisms like <i>Staphylococcus aureus<\/i>. It is essential for advanced anti-aging and sensitive skin formulations.<\/div>\n<\/div>\n<div class=\"mb-[60px]\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"floating-tool-eOtU8Y\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"answer-action-bar-MECk3C bottom-action-bar-wrapper-EmBxFl large-space-VAvLxB answer-action-bar\" data-testid=\"message_action_bar\">\n<div class=\"container-x3q9t6 container-WoBT2A bottom-action-bar-t2Ap99\">\n<div class=\"left-Jj7zwC\">\n<div class=\"bp5-overflow-list container-uvaRiZ align-start-A9MbD9 inner-rETKn9\"><\/div>\n<\/div>\n<\/div>\n<\/div>","protected":false},"featured_media":12956,"template":"","meta":[],"etheme_brands":[],"product_cat":[20,22],"product_tag":[],"class_list":{"0":"post-13534","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-licorice-root-extract","7":"product_cat-brightening","9":"first","10":"instock","11":"featured","12":"shipping-taxable","13":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Licochalcone A Suppliers &amp; Wholesalers | Cosmetic Grade - HuaTai<\/title>\n<meta name=\"description\" content=\"Reliable China Skincare Ingredients Source Factory &amp; Supplier of high-purity Licochalcone A. 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