{"id":15750,"date":"2026-11-11T02:16:08","date_gmt":"2026-11-11T02:16:08","guid":{"rendered":"https:\/\/www.natural-huatai.com\/?p=15750"},"modified":"2026-11-11T02:16:10","modified_gmt":"2026-11-11T02:16:10","slug":"centella-asiatica-extract-in-cosmetics-how-to-qualify-a-replacement-grade","status":"publish","type":"post","link":"https:\/\/www.natural-huatai.com\/fr\/centella-asiatica-extract-in-cosmetics-how-to-qualify-a-replacement-grade\/","title":{"rendered":"Extrait de Centella Asiatica dans les Cosm\u00e9tiques : Comment Qualifier un Grade de Remplacement"},"content":{"rendered":"
\n

\n Quand un nouveau fournisseur propose un devis Extrait de Centella asiatica<\/span>, r\u00e9cup\u00e9rez le dossier d'approbation du grade d\u00e9j\u00e0 utilis\u00e9. Recherchez les conditions que l'\u00e9chantillon original devait remplir. La mati\u00e8re premi\u00e8re pouvait n\u00e9cessiter une teneur minimale en mad\u00e9cassoside. Le s\u00e9rum pouvait devoir rester limpide pendant le stockage. La cr\u00e8me finie pouvait avoir \u00e9t\u00e9 test\u00e9e pour \u00e9tayer une all\u00e9gation d'hydratation. Chaque condition n\u00e9cessite une v\u00e9rification diff\u00e9rente avant que le remplacement puisse \u00eatre approuv\u00e9.<\/span>\n <\/p>\n\n \n

\n Commencez par le dosage qui comptait dans l'approbation originale\n <\/h3>\n

\n Si la sp\u00e9cification originale fixe un minimum de mad\u00e9cassoside<\/span>, demandez le r\u00e9sultat du mad\u00e9cassoside sur le lot propos\u00e9. Un chiffre plus \u00e9lev\u00e9 pour les triterp\u00e8nes totaux laisse cette exigence ouverte. Le mad\u00e9cassoside, l'asiaticoside, l'acide mad\u00e9cassique et l'acide asiatique peuvent \u00eatre mesur\u00e9s s\u00e9par\u00e9ment par HPLC, alors demandez les r\u00e9sultats individuels lorsque la sp\u00e9cification en d\u00e9pend (Shen et al., 2014).\n <\/p>\n

\n Demandez \u00e0 votre fournisseur d'extrait de Centella asiatica comment le total a \u00e9t\u00e9 d\u00e9termin\u00e9 et quels compos\u00e9s il couvre. \u00ab Test\u00e9 par HPLC \u00bb<\/span> nomme la technique. Le rapport doit toujours identifier ce qui a \u00e9t\u00e9 mesur\u00e9 et si le pourcentage est sur une base s\u00e8che ou s'applique au mat\u00e9riau tel que fourni. Si les deux fournisseurs rapportent sur des bases diff\u00e9rentes, r\u00e9solvez cela avant d'utiliser les chiffres pour d\u00e9finir l'ajout d'essai.\n <\/p>\n

\n Un ratio d'extrait doit figurer sur une ligne s\u00e9par\u00e9e. Demandez dans quel sens il est \u00e9crit et s'il fait r\u00e9f\u00e9rence \u00e0 l'extrait avant l'ajout d'un support. Il d\u00e9crit la relation entre la mati\u00e8re v\u00e9g\u00e9tale de d\u00e9part et l'extrait. Pour une formule qui n\u00e9cessite une teneur minimale en marqueur, le laboratoire a toujours besoin du dosage. Dans la mesure du possible, comparez les r\u00e9sultats r\u00e9els du lot pour les grades originaux et propos\u00e9s.<\/strong> Une limite de sp\u00e9cification vous indique ce que le fournisseur acceptera. Le r\u00e9sultat du lot vous indique ce que le laboratoire est sur le point de peser.\n <\/p>\n\n \n

\n Gardez le premier essai proche de la formule approuv\u00e9e\n <\/h3>\n

\n V\u00e9rifiez la composition compl\u00e8te avant d'ajouter l'\u00e9chantillon.<\/span> Une poudre d'extrait de Centella asiatica peut contenir un support, et un grade liquide peut introduire de l'eau, de la glyc\u00e9rine ou un autre solvant. Si le liquide fournit de la glyc\u00e9rine, incluez-la dans le total de la formule. Sinon, un changement dans la sensation du s\u00e9rum pourrait \u00eatre difficile \u00e0 attribuer \u00e0 l'extrait lui-m\u00eame.\n <\/p>\n

\n Effectuez le premier essai au pH cible existant et suivez la proc\u00e9dure de m\u00e9lange originale dans la mesure du possible. Comparez-le \u00e0 la formule approuv\u00e9e au m\u00eame \u00e2ge apr\u00e8s fabrication. Dans un s\u00e9rum limpide, notez la limpidit\u00e9 et la couleur, et v\u00e9rifiez la pr\u00e9sence de s\u00e9diments pendant le stockage. Une cr\u00e8me opaque peut tol\u00e9rer un changement de couleur qui ferait \u00e9chouer la norme d'apparence du s\u00e9rum limpide. D\u00e9finissez cette limite avant de d\u00e9cider si le candidat est retenu.\n <\/p>\n

\n Si le s\u00e9rum devient trouble, notez quand le trouble appara\u00eet pour la premi\u00e8re fois. Un pr\u00e9m\u00e9lange trouble vous donne une raison de revoir l'\u00e9tape du solvant et de la dispersion. Un pr\u00e9m\u00e9lange limpide qui ne devient trouble qu'apr\u00e8s ajout met le pH de travail, les autres ingr\u00e9dients et l'ordre d'addition sur la liste \u00e0 \u00e9tudier. Le calendrier aide \u00e0 affiner le prochain essai. Changer l'extrait, le pH et l'\u00e9paississant ensemble rend plus difficile de savoir quel changement a compt\u00e9.<\/span>\n <\/p>\n\n \n

\n V\u00e9rifiez l'all\u00e9gation par rapport au test qui la soutient\n <\/h3>\n

\n Un lot peut respecter les limites de marqueurs et donner un s\u00e9rum stable tout en laissant la question de l'efficacit\u00e9 ouverte. Ratz-\u0141yko et al. (2016) ont mesur\u00e9 l'hydratation de la peau et la perte d'eau trans\u00e9pidermique dans des formulations cosm\u00e9tiques contenant de l'extrait de Centella asiatica. Ces r\u00e9sultats s'appliquent \u00e0 l'extrait et aux formules test\u00e9es dans cette \u00e9tude.\n <\/p>\n

\n Pour un remplacement, commencez par votre propre rapport de produit fini. Si l'all\u00e9gation originale repose sur une lecture d'hydratation \u00e0 un moment donn\u00e9, utilisez ce point final et ce point temporel lors de la planification d'une comparaison cibl\u00e9e. Un changement mat\u00e9riel dans le profil du marqueur ou le support donne \u00e0 l'\u00e9quipe une raison concr\u00e8te d'envisager de re-tester.<\/span> Le dosage \u00e9tablit ce qui est entr\u00e9 dans le lot. Le test d'hydratation aborde ce que le produit fini a d\u00e9livr\u00e9.\n <\/p>\n\n \n

\n Foire aux questions\n <\/h3>\n \n \n \n \n \n \n \n
Question<\/th>\n Conseils \/ R\u00e9ponse<\/th>\n <\/tr>\n <\/thead>\n
Deux extraits portant le m\u00eame nom INCI peuvent-ils \u00eatre utilis\u00e9s au m\u00eame taux d'addition ?<\/td>\n V\u00e9rifiez d'abord la teneur en marqueurs et la composition fournie. Si le taux d'addition original a \u00e9t\u00e9 fix\u00e9 pour fournir un niveau de marqueur particulier, utilisez le dosage tel que fourni du candidat pour d\u00e9finir la dose d'essai. V\u00e9rifiez ensuite que la formule r\u00e9sultante r\u00e9pond toujours \u00e0 ses crit\u00e8res d'acceptation.<\/td>\n <\/tr>\n
L'asiaticoside purifi\u00e9 peut-il remplacer l'extrait de Centella asiatica ?<\/td>\n Il peut fournir du mad\u00e9cassoside. Si le grade original a \u00e9t\u00e9 approuv\u00e9 sur la base de plusieurs marqueurs, la correspondance d'un compos\u00e9 ne couvre qu'une partie de la sp\u00e9cification. Examinez pourquoi l'extrait a \u00e9t\u00e9 s\u00e9lectionn\u00e9 pour la formule avant de d\u00e9cider comment tester le changement.<\/td>\n <\/tr>\n
Que doit conserver les achats une fois le remplacement approuv\u00e9 ?<\/td>\n Conservez le grade du fournisseur, la partie de la plante, la composition du support ou du solvant, les limites de marqueurs convenues, la m\u00e9thode de dosage et la base de rapport avec la sp\u00e9cification approuv\u00e9e. Classez le COA du lot d'essai avec le dossier de la formule afin que la prochaine livraison puisse \u00eatre v\u00e9rifi\u00e9e par rapport au mat\u00e9riau que le laboratoire a qualifi\u00e9.<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n \n

\n R\u00e9f\u00e9rences\n <\/h3>\n
    \n
  • \n Ratz-\u0141yko, A., Arct, J., & Pytkowska, K. (2016). Propri\u00e9t\u00e9s hydratantes et anti-inflammatoires des formulations cosm\u00e9tiques contenant de l'extrait de Centella asiatica. Indian Journal of Pharmaceutical Sciences<\/em>, 78(1), 27\u201333.\n <\/li>\n
  • \n Shen, Q., Yu, L. S., Zhou, H., & Zeng, S. (2014). D\u00e9termination simultan\u00e9e du mad\u00e9cassoside, de l'asiaticoside et de leurs aglycones dans les extraits de Centella asiatica (L.) Urban par RP-HPLC. Journal of Zhejiang University (Medical Sciences)<\/em>, 43(2), 135\u2013140.\n <\/li>\n <\/ul>\n\n<\/div>","protected":false},"excerpt":{"rendered":"

    Lorsqu'un nouveau fournisseur propose un devis pour l'extrait de Centella asiatica, extrayez le dossier d'approbation pour le grade d\u00e9j\u00e0 utilis\u00e9. Recherchez les conditions de l'\u00e9chantillon original\u2026<\/p>","protected":false},"author":1,"featured_media":15751,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[357],"tags":[],"class_list":["post-15750","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-product-updates"],"yoast_head":"\nCentella Asiatica Extract in Cosmetics: How to Qualify a Replacement Grade - Natural huatai<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.natural-huatai.com\/fr\/centella-asiatica-extract-in-cosmetics-how-to-qualify-a-replacement-grade\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Centella Asiatica Extract in Cosmetics: How to Qualify a Replacement Grade\" \/>\n<meta property=\"og:description\" content=\"When a new supplier quotes Centella asiatica extract, pull the approval record for the grade already in use. 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