{"id":15514,"date":"2026-09-16T08:16:38","date_gmt":"2026-09-16T08:16:38","guid":{"rendered":"https:\/\/www.natural-huatai.com\/?p=15514"},"modified":"2026-09-16T08:16:40","modified_gmt":"2026-09-16T08:16:40","slug":"formulating-licochalcone-a-glycyrrhiza-inflata-extract","status":"publish","type":"post","link":"https:\/\/www.natural-huatai.com\/fr\/formulating-licochalcone-a-glycyrrhiza-inflata-extract\/","title":{"rendered":"Formulation de la Licochalcone A : Extrait de Glycyrrhiza Inflata"},"content":{"rendered":"<div style=\"max-width: 100%; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; line-height: 1.6; color: #333333; background-color: #ffffff; padding: 20px; box-sizing: border-box;\">\n    <div style=\"background-color: #f8fafc; padding: 20px; border-radius: 8px; border: 1px solid #e2e8f0; margin-bottom: 30px;\">\n        <h3 style=\"color: #0f172a; font-size: 18px; margin-top: 0; margin-bottom: 15px;\">Table des mati\u00e8res<\/h3>\n        <ul style=\"list-style-type: none; padding-left: 0; margin: 0;\">\n            <li style=\"margin-bottom: 8px;\"><a href=\"#distinction\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">La distinction Licochalcone A : Nrf2 et COX\/LOX<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#specifications\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Sp\u00e9cifications physico-chimiques (R\u00e9f\u00e9rentiels COA)<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#efficacy\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Efficacit\u00e9 in vitro : les chiffres concrets<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#synergies\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Synergies de formulation : ciblage du PIE et de l'\u00e9ryth\u00e8me<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#solubility\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Param\u00e8tres de solubilit\u00e9 et traitement de base<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#faqs\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Approvisionnement fournisseur : 8 FAQ \u00e0 haute fr\u00e9quence (Optimis\u00e9 G\u00e9ographiquement)<\/a><\/li>\n            <li style=\"margin-bottom: 0;\"><a href=\"#references\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">R\u00e9f\u00e9rences faisant autorit\u00e9<\/a><\/li>\n        <\/ul>\n    <\/div>\n\n    <h2 id=\"distinction\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">La distinction Licochalcone A : Nrf2 et COX\/LOX<\/h2>\n    <p style=\"margin-bottom: 15px;\">Clarifions le m\u00e9canisme. <em>Glycyrrhiza Inflata<\/em> est compl\u00e8tement distinct de <em>Glycyrrhiza Glabra<\/em>.<\/p>\n    <p style=\"margin-bottom: 15px;\">Vous extrayez <em>G. glabra<\/em> pour la Glabridine. Cela cible la tyrosinase. Vous extrayez <em>G. inflata<\/em> pour le Licochalcone A. La cible ici est l'inflammation cutan\u00e9e s\u00e9v\u00e8re. Les agents apaisants standards ne font que masquer les rougeurs. Le Licochalcone A agit diff\u00e9remment. Il agit comme un <span style=\"color: #b91c1c; font-weight: bold;\">double inhibiteur<\/span>, bloquant \u00e0 la fois les voies de la cyclooxyg\u00e9nase-2 (COX-2) et de la lipoxyg\u00e9nase (LOX). Cela stoppe la synth\u00e8se de la Prostaglandine E2 (PGE2) et de la Leucotri\u00e8ne B4 (LTB4) \u00e0 la source. Le r\u00e9sultat ? Une att\u00e9nuation rapide de la vasodilatation.<\/p>\n    <p style=\"margin-bottom: 15px;\">Mais son v\u00e9ritable pouvoir r\u00e9side dans la d\u00e9fense cellulaire. Il ne se contente pas de neutraliser les radicaux libres en surface. Il active la <span style=\"color: #047857; font-weight: bold; font-size: 1.1em;\">voie de signalisation Nrf2\/ARE<\/span>Cela force les cellules de la peau \u00e0 r\u00e9guler \u00e0 la hausse leurs propres enzymes antioxydantes endog\u00e8nes, comme l'H\u00e8me Oxyg\u00e9nase-1 (HO-1). C'est une intervention au niveau des r\u00e9cepteurs. C'est pourquoi les dermatologues le sp\u00e9cifient pour les protocoles de rosac\u00e9e et la r\u00e9cup\u00e9ration post-proc\u00e9dure.<\/p>\n\n    <h2 id=\"specifications\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Sp\u00e9cifications physico-chimiques (R\u00e9f\u00e9rentiels COA)<\/h2>\n    <p style=\"margin-bottom: 15px;\">S'appuyer sur des extraits de plantes non standardis\u00e9s ruine la coh\u00e9rence de la formule. La pr\u00e9cision exige une v\u00e9rification par dosage. Comparez le COA de votre mati\u00e8re premi\u00e8re \u00e0 ces m\u00e9triques de base.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Parameter<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Sp\u00e9cification Standard<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">M\u00e9thode de test \/ Remarques<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Marqueur actif<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #047857; font-weight: bold;\">Licochalcone A \u2265 20,0 %<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">HPLC<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Appearance<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Poudre jaune \u00e0 jaune brun\u00e2tre<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Visuel. La teinte jaune intense est intrins\u00e8que aux chalcones.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Solubility<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Insoluble dans l'eau. Soluble dans le propyl\u00e8ne glycol, l'\u00e9thanol.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Validation physique.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Loss on Drying<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\u2264 5,0 %<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">105\u00b0C pendant 2 heures.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Teneur en cendres<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\u2264 2,0 %<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Calcination \u00e0 800\u00b0C.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Heavy Metals<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #b91c1c; font-weight: bold;\">\u2264 10 ppm Total. (Pb \u2264 2ppm, As \u2264 1ppm)<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">ICP-MS. Obligatoire pour une conformit\u00e9 stricte FDA\/UE.<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"efficacy\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Efficacit\u00e9 in vitro : les chiffres concrets<\/h2>\n    <p style=\"margin-bottom: 15px;\">Les all\u00e9gations marketing ne r\u00e9parent pas les barri\u00e8res compromises. Les donn\u00e9es r\u00e9elles le font. Examinons les performances en laboratoire.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Cible \/ Voie<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Valeur d'efficacit\u00e9<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Pertinence clinique<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Production de PGE2<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">IC50 \u2248 1,8 \u03bcM<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">R\u00e9duit consid\u00e9rablement l'\u00e9ryth\u00e8me induit par les UV. Att\u00e9nue la vasodilatation capillaire aigu\u00eb.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Cutibacterium acnes<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">MIC 5,0 \u2013 15,0 \u03bcg\/mL<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Effet bact\u00e9ricide direct. Cible l'acn\u00e9 inflammatoire sans desquamation acide.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Activation de Nrf2<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">Induction de HO-1 \u00e0 5-10 \u03bcM<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Augmente la d\u00e9fense antioxydante intracellulaire. Prot\u00e8ge contre la peroxydation lipidique secondaire.<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"synergies\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Synergies de formulation : ciblage du PIE et de l'\u00e9ryth\u00e8me<\/h2>\n    <p style=\"margin-bottom: 15px;\">Les actifs doivent collaborer dans la matrice. La tendance clinique actuelle privil\u00e9gie l'intervention non destructive. Vous devez associer strat\u00e9giquement Glycyrrhiza Inflata.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Partenaire de synergie<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">M\u00e9canisme d'interaction<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Indication cible<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Tranexamic Acid<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">L'acide tranexamique bloque le plasminog\u00e8ne. Le Licochalcone A supprime la COX-2. Ensemble, ils bloquent l'angiogen\u00e8se.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #b91c1c; font-weight: bold;\">\u00c9ryth\u00e8me post-inflammatoire (PIE)<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Centella Asiatica (Mad\u00e9cassoside)<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Le mad\u00e9cassoside acc\u00e9l\u00e8re la synth\u00e8se du collag\u00e8ne III. Le Licochalcone A emp\u00eache les signaux inflammatoires de retarder la r\u00e9paration.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">R\u00e9cup\u00e9ration post-proc\u00e9dure<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Oat Beta-Glucan<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Le b\u00eata-glucane fournit un blindage de surface de haut poids mol\u00e9culaire. Le Licochalcone A coupe les cascades inflammatoires profondes.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Dermatite chronique<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"solubility\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Param\u00e8tres de solubilit\u00e9 et traitement de base<\/h2>\n    <p style=\"margin-bottom: 15px;\">Le Licochalcone A d\u00e9teste l'eau. Il est profond\u00e9ment hydrophobe. L'ajouter directement \u00e0 une phase aqueuse ? Il pr\u00e9cipite instantan\u00e9ment. La biodisponibilit\u00e9 tombe \u00e0 z\u00e9ro.<\/p>\n    <ul style=\"padding-left: 20px; margin-bottom: 20px;\">\n        <li style=\"margin-bottom: 10px;\"><strong>Solvent Selection:<\/strong> Pr\u00e9-disperser la poudre. Utiliser du propyl\u00e8ne glycol, du butyl\u00e8ne glycol ou du PEG-400. Besoin dans un s\u00e9rum transparent ? L'\u00e9thoxydiglycol (Transcutol) combin\u00e9 \u00e0 un solubilisant comme le Polysorbate 20 est obligatoire.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>Protocoles de temp\u00e9rature :<\/strong> Chauffer votre phase de glycol \u00e0 45\u00b0C \u2013 55\u00b0C. Assurer une dissolution compl\u00e8te. <span style=\"color: #b91c1c; font-weight: bold;\">Ne pas d\u00e9passer 65\u00b0C.<\/span> Une chaleur \u00e9lev\u00e9e d\u00e9grade les structures de chalcone.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>Int\u00e9gration de phase :<\/strong> Refroidir le lot primaire. Introduire l'actif solubilis\u00e9 dans l'\u00e9mulsion uniquement lorsque les temp\u00e9ratures descendent en dessous de 45\u00b0C.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>pH Stability:<\/strong> Maintenez le pH de votre formule strictement entre <span style=\"color: #047857; font-weight: bold; font-size: 1.1em;\">4,5 et 6,5<\/span>Les environnements tr\u00e8s alcalins (pH &gt; 7,5) d\u00e9truisent le Licochalcone A. L'extrait virera visiblement au brun fonc\u00e9.<\/li>\n    <\/ul>\n\n    <h2 id=\"faqs\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Approvisionnement fournisseur : 8 FAQ \u00e0 haute fr\u00e9quence (Optimis\u00e9 G\u00e9ographiquement)<\/h2>\n    <div style=\"margin-bottom: 25px;\">\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Quelle est la diff\u00e9rence fondamentale entre les extraits de racine de Glycyrrhiza Inflata et de Glycyrrhiza Glabra ?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Diff\u00e9rentes esp\u00e8ces ciblent diff\u00e9rentes voies. <em>G. glabra<\/em> fournit la Glabridine pour inhiber la tyrosinase (blanchiment). <em>G. inflata<\/em> fournit le Licochalcone A. Il cible les voies inflammatoires COX\/LOX et agit comme un puissant r\u00e9ducteur d'\u00e9ryth\u00e8me.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Comment les formulateurs solubilisent-ils le Licochalcone A de haute puret\u00e9 dans les s\u00e9rums \u00e0 base d'eau ?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">L'eau seule \u00e9choue. Vous devez pr\u00e9-dissoudre la poudre dans un syst\u00e8me de glycol (comme le butyl\u00e8ne glycol). Pour des s\u00e9rums aqueux compl\u00e8tement transparents, un m\u00e9lange \u00e0 haut cisaillement avec des tensioactifs (PEG-40 Huile de ricin hydrog\u00e9n\u00e9e) est requis avant l'int\u00e9gration aqueuse.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Quelle est la plage de dosage optimale pour les produits de soins de la peau sans rin\u00e7age ?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Maintenez-la entre <span style=\"color: #047857; font-weight: bold;\">0,05 % et 0,5 %<\/span> pour les \u00e9mulsions sans rin\u00e7age. L'entretien quotidien de la barri\u00e8re n\u00e9cessite environ 0,1 %. Les traitements pour le soulagement aigu de l'\u00e9ryth\u00e8me ou le PIE n\u00e9cessitent 0,3 % \u00e0 0,5 %.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">L'extrait de Glycyrrhiza Inflata pr\u00e9sente-t-il des risques de phototoxicit\u00e9 ?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Non. Des tests en laboratoire confirment l'absence de phototoxicit\u00e9. Des donn\u00e9es revues par des pairs montrent en fait qu'il active Nrf2. Cela retarde l'\u00e9ryth\u00e8me induit par les UV et pr\u00e9vient l'apoptose cellulaire d\u00e9clench\u00e9e par les UV.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Comment cet extrait se compare-t-il au Cutibacterium acnes par rapport aux acides standards ?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">L'acide salicylique d\u00e9colle les cellules mortes de la peau pour d\u00e9gager le follicule. Glycyrrhiza Inflata attaque directement la bact\u00e9rie. Il a une MIC de 5,0 \u2013 15,0 \u03bcg\/mL contre <em>C. acnes<\/em>Vous obtenez une action antibact\u00e9rienne sans le pelage caus\u00e9 par les AHA\/BHA.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Qu'est-ce qui provoque le changement de couleur de l'extrait dans certaines formulations ?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">L'alcalinit\u00e9 d\u00e9truit les chalcones. Si votre formule d\u00e9passe un pH de 7,0, l'extrait subit une ouverture de cycle. Il devient brun rouge\u00e2tre. L'efficacit\u00e9 dispara\u00eet. Verrouillez votre tampon de pH entre 4,5 et 6,5.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Y a-t-il des probl\u00e8mes de conformit\u00e9 aux m\u00e9taux lourds avec les mati\u00e8res premi\u00e8res d\u00e9riv\u00e9es de la r\u00e9glisse ?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Oui. Les racines de r\u00e9glisse bioaccumulent agressivement les m\u00e9taux lourds du sol. Les extraits de qualit\u00e9 inf\u00e9rieure \u00e9chouent aux tests de s\u00e9curit\u00e9. Exigez un COA prouvant que les m\u00e9taux lourds totaux sont \u2264 10 ppm gr\u00e2ce \u00e0 des tests ICP-MS stricts.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Peut-il \u00eatre formul\u00e9 directement aux c\u00f4t\u00e9s de l'acide L-ascorbique (vitamine C) \u00e0 faible pH ?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Cela n\u00e9cessite une formulation avanc\u00e9e. Bien que la structure chimique du Licochalcone A survive \u00e0 un pH bas, la forte acidit\u00e9 d'un s\u00e9rum \u00e0 la vitamine C \u00e0 15% (pH 3,0 \u2013 3,5) r\u00e9duit consid\u00e9rablement sa solubilit\u00e9. Sans support de solvant avanc\u00e9 (comme l'\u00e9thoxydiglycol), l'actif cristallise et pr\u00e9cipite hors du s\u00e9rum.<\/p>\n    <\/div>\n\n    <h2 id=\"references\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px; border-top: 1px solid #e2e8f0; padding-top: 20px;\">R\u00e9f\u00e9rences faisant autorit\u00e9<\/h2>\n    <ol style=\"padding-left: 20px; font-size: 14px; color: #475569;\">\n        <li style=\"margin-bottom: 8px;\">Kolbe, L., et al. (2006). \u00ab Efficacit\u00e9 anti-inflammatoire du Licochalcone A : corr\u00e9lation entre la puissance clinique et les effets in vitro \u00bb. <em>Archives de recherche dermatologique<\/em>, 298(1), 23-30.<\/li>\n        <li style=\"margin-bottom: 8px;\">Shibata, S. (2000). \u00ab Un m\u00e9dicament \u00e0 travers les mill\u00e9naires : pharmacognosie, chimie et pharmacologie de la r\u00e9glisse \u00bb. <em>Yakugaku Zasshi<\/em>, 120(10), 849-862.<\/li>\n        <li style=\"margin-bottom: 8px;\">Yin, Z., et al. (2020). \u00ab Le Licochalcone A inhibe les r\u00e9ponses inflammatoires par la suppression des voies NF-\u03baB et MAPK \u00bb. <em>Journal international de m\u00e9decine mol\u00e9culaire<\/em>, 45(4), 1187-1196.<\/li>\n        <li style=\"margin-bottom: 8px;\">Wu, L., et al. (2015). \u00ab Le Licochalcone A active la signalisation de l'\u00e9l\u00e9ment de r\u00e9ponse antioxydante Nrf2\u2026 \u00bb <em>European Journal of Pharmacology<\/em>, 761, 33-41.<\/li>\n    <\/ol>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Table des mati\u00e8res 1. La distinction Licochalcone A : Nrf2 et COX\/LOX 2. Sp\u00e9cifications physico-chimiques (R\u00e9f\u00e9rences COA) 3. Efficacit\u00e9 in vitro : les chiffres concrets 4. Synergies de formulation :\u2026<\/p>","protected":false},"author":1,"featured_media":14737,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[357],"tags":[],"class_list":["post-15514","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-product-updates"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Formulating Licochalcone A: Glycyrrhiza Inflata Extract - Natural huatai<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.natural-huatai.com\/fr\/formulating-licochalcone-a-glycyrrhiza-inflata-extract\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Formulating Licochalcone A: Glycyrrhiza Inflata Extract\" \/>\n<meta property=\"og:description\" content=\"Table of Contents 1. 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