{"id":15750,"date":"2026-11-11T02:16:08","date_gmt":"2026-11-11T02:16:08","guid":{"rendered":"https:\/\/www.natural-huatai.com\/?p=15750"},"modified":"2026-11-11T02:16:10","modified_gmt":"2026-11-11T02:16:10","slug":"centella-asiatica-extract-in-cosmetics-how-to-qualify-a-replacement-grade","status":"publish","type":"post","link":"https:\/\/www.natural-huatai.com\/es\/centella-asiatica-extract-in-cosmetics-how-to-qualify-a-replacement-grade\/","title":{"rendered":"Extracto de Centella Asi\u00e1tica en Cosm\u00e9tica: C\u00f3mo Calificar un Grado de Reemplazo"},"content":{"rendered":"
\n

\n Cuando un nuevo proveedor cotiza Extracto de Centella asi\u00e1tica<\/span>, recupere el registro de aprobaci\u00f3n del grado que ya est\u00e1 en uso. Busque las condiciones que la muestra original tuvo que cumplir. La materia prima puede haber necesitado un contenido m\u00ednimo de madecas\u00f3sido. El s\u00e9rum puede haber tenido que permanecer transparente durante el almacenamiento. La crema terminada puede haber sido probada para respaldar una afirmaci\u00f3n de hidrataci\u00f3n. Cada condici\u00f3n requiere una verificaci\u00f3n diferente antes de que el reemplazo pueda ser aprobado.<\/span>\n <\/p>\n\n \n

\n Comience con el Ensayo que Import\u00f3 en la Aprobaci\u00f3n Original\n <\/h3>\n

\n Si la especificaci\u00f3n original establece un m\u00ednimo de madecas\u00f3sido<\/span>, solicite el resultado de madecas\u00f3sido del lote propuesto. Una cifra m\u00e1s alta para los triterpenos totales deja ese requisito abierto. El madecas\u00f3sido, la asiatic\u00f3sido, el \u00e1cido madec\u00e1sico y el \u00e1cido asi\u00e1tico se pueden medir por separado por HPLC, as\u00ed que solicite los resultados individuales cuando la especificaci\u00f3n dependa de ellos (Shen et al., 2014).\n <\/p>\n

\n Pregunte a su proveedor de extracto de Centella asi\u00e1tica c\u00f3mo se determin\u00f3 el total y qu\u00e9 compuestos cubre. \u201cProbado por HPLC\u201d<\/span> nombra la t\u00e9cnica. El informe a\u00fan debe identificar qu\u00e9 se midi\u00f3 y si el porcentaje se basa en materia seca o se aplica al material tal como se suministra. Si los dos proveedores informan sobre bases diferentes, resuelva eso antes de usar los n\u00fameros para establecer la adici\u00f3n de prueba.\n <\/p>\n

\n Una relaci\u00f3n de extracto pertenece a una l\u00ednea separada. Pregunte de qu\u00e9 manera est\u00e1 escrita y si se refiere al extracto antes de la adici\u00f3n de un portador. Describe la relaci\u00f3n entre el material vegetal de partida y el extracto. Para una f\u00f3rmula que requiere un contenido m\u00ednimo de marcador, el laboratorio a\u00fan necesita el ensayo. Siempre que sea posible, compare los resultados reales del lote para los grados original y propuesto.<\/strong> Un l\u00edmite de especificaci\u00f3n le dice lo que el proveedor aceptar\u00e1. El resultado del lote le dice lo que el laboratorio est\u00e1 a punto de pesar.\n <\/p>\n\n \n

\n Mantenga la Primera Prueba Cercana a la F\u00f3rmula Aprobada\n <\/h3>\n

\n Verifique la composici\u00f3n completa antes de agregar la muestra.<\/span> Un polvo de extracto de Centella asi\u00e1tica puede contener un portador, y un grado l\u00edquido puede introducir agua, glicerina u otro disolvente. Si el l\u00edquido suministra glicerina, incl\u00fayala en el total de la f\u00f3rmula. De lo contrario, un cambio en la sensaci\u00f3n del s\u00e9rum podr\u00eda ser dif\u00edcil de atribuir al extracto en s\u00ed.\n <\/p>\n

\n Realice la primera prueba al objetivo de pH existente y siga el procedimiento de mezcla original donde sea pr\u00e1ctico. Comp\u00e1relo con la f\u00f3rmula aprobada a la misma edad despu\u00e9s de la fabricaci\u00f3n. En un s\u00e9rum transparente, registre la claridad y el color, y verifique si hay sedimentos durante el almacenamiento. Una crema opaca puede tolerar un cambio de color que har\u00eda fallar el est\u00e1ndar de apariencia del s\u00e9rum transparente. Establezca ese l\u00edmite antes de decidir si el candidato pasa.\n <\/p>\n

\n Si el s\u00e9rum se vuelve turbio, anote cu\u00e1ndo aparece la turbidez por primera vez. Una premezcla turbia le da una raz\u00f3n para revisar el disolvente y el paso de dispersi\u00f3n. Una premezcla transparente que solo se vuelve turbia despu\u00e9s de la adici\u00f3n pone el pH de trabajo, los otros ingredientes y el orden de adici\u00f3n en la lista para investigar. El momento ayuda a reducir la pr\u00f3xima prueba. Cambiar el extracto, el pH y el espesante juntos hace que sea m\u00e1s dif\u00edcil saber qu\u00e9 cambio import\u00f3.<\/span>\n <\/p>\n\n \n

\n Verifique la Afirmaci\u00f3n Contra la Prueba que la Respalda\n <\/h3>\n

\n Un lote puede cumplir los l\u00edmites de marcadores y dar un s\u00e9rum estable, dejando abierta la cuesti\u00f3n de la eficacia. Ratz-\u0141yko et al. (2016) midieron la hidrataci\u00f3n de la piel y la p\u00e9rdida de agua transepid\u00e9rmica en formulaciones cosm\u00e9ticas que conten\u00edan extracto de Centella asi\u00e1tica. Esos hallazgos se aplican al extracto y a las f\u00f3rmulas probadas en ese estudio.\n <\/p>\n

\n Para un reemplazo, comience con su propio informe de producto terminado. Si la afirmaci\u00f3n original se basa en una lectura de hidrataci\u00f3n en un momento particular, use ese punto final y punto de tiempo al planificar una comparaci\u00f3n enfocada. Un cambio material en el perfil del marcador o el portador le da al equipo una raz\u00f3n concreta para considerar volver a probar.<\/span> El ensayo establece lo que entr\u00f3 en el lote. La prueba de hidrataci\u00f3n aborda lo que entreg\u00f3 el producto terminado.\n <\/p>\n\n \n

\n Preguntas Frecuentes\n <\/h3>\n \n \n \n \n \n \n \n
Pregunta<\/th>\n Gu\u00eda \/ Respuesta<\/th>\n <\/tr>\n <\/thead>\n
\u00bfSe pueden usar dos extractos con el mismo nombre INCI a la misma tasa de adici\u00f3n?<\/td>\n Verifique primero el contenido del marcador y la composici\u00f3n suministrada. Si la tasa de adici\u00f3n original se estableci\u00f3 para entregar un nivel de marcador particular, use el ensayo tal como se suministra del candidato para establecer la dosis de prueba. Luego verifique que la f\u00f3rmula resultante a\u00fan cumpla sus criterios de aceptaci\u00f3n.<\/td>\n <\/tr>\n
\u00bfPuede el madecas\u00f3sido purificado reemplazar el extracto de Centella asi\u00e1tica?<\/td>\n Puede suministrar madecas\u00f3sido. Si el grado original fue aprobado contra varios marcadores, igualar un compuesto cubre solo una parte de la especificaci\u00f3n. Revise para qu\u00e9 se seleccion\u00f3 el extracto en la f\u00f3rmula antes de decidir c\u00f3mo probar el cambio.<\/td>\n <\/tr>\n
\u00bfQu\u00e9 debe retener compras una vez que se aprueba el reemplazo?<\/td>\n Conserve el grado del proveedor, la parte de la planta, la composici\u00f3n del portador o disolvente, los l\u00edmites de marcadores acordados, el m\u00e9todo de ensayo y la base de informes con la especificaci\u00f3n aprobada. Archive el COA del lote de prueba con el registro de la f\u00f3rmula para que la pr\u00f3xima entrega pueda verificarse con el material que el laboratorio calific\u00f3.<\/td>\n <\/tr>\n <\/tbody>\n <\/table>\n\n \n

\n Referencias\n <\/h3>\n
    \n
  • \n Ratz-\u0141yko, A., Arct, J., & Pytkowska, K. (2016). Propiedades hidratantes y antiinflamatorias de formulaciones cosm\u00e9ticas que contienen extracto de Centella asi\u00e1tica. Indian Journal of Pharmaceutical Sciences<\/em>, 78(1), 27\u201333.\n <\/li>\n
  • \n Shen, Q., Yu, L. S., Zhou, H., & Zeng, S. (2014). Determinaci\u00f3n simult\u00e1nea de madecas\u00f3sido, asiatic\u00f3sido y sus agliconas en extractos de Centella asi\u00e1tica (L.) Urban por RP-HPLC. Journal of Zhejiang University (Medical Sciences)<\/em>, 43(2), 135\u2013140.\n <\/li>\n <\/ul>\n\n<\/div>","protected":false},"excerpt":{"rendered":"

    Cuando un nuevo proveedor cotice extracto de Centella asi\u00e1tica, extraiga el registro de aprobaci\u00f3n para el grado ya en uso. Busque las condiciones de la muestra original\u2026<\/p>","protected":false},"author":1,"featured_media":15751,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[357],"tags":[],"class_list":["post-15750","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-product-updates"],"yoast_head":"\nCentella Asiatica Extract in Cosmetics: How to Qualify a Replacement Grade - Natural huatai<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.natural-huatai.com\/es\/centella-asiatica-extract-in-cosmetics-how-to-qualify-a-replacement-grade\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Centella Asiatica Extract in Cosmetics: How to Qualify a Replacement Grade\" \/>\n<meta property=\"og:description\" content=\"When a new supplier quotes Centella asiatica extract, pull the approval record for the grade already in use. 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