{"id":15514,"date":"2026-09-16T08:16:38","date_gmt":"2026-09-16T08:16:38","guid":{"rendered":"https:\/\/www.natural-huatai.com\/?p=15514"},"modified":"2026-09-16T08:16:40","modified_gmt":"2026-09-16T08:16:40","slug":"formulating-licochalcone-a-glycyrrhiza-inflata-extract","status":"publish","type":"post","link":"https:\/\/www.natural-huatai.com\/de\/formulating-licochalcone-a-glycyrrhiza-inflata-extract\/","title":{"rendered":"Formulierung von Licochalcon A: Glycyrrhiza Inflata Extrakt"},"content":{"rendered":"<div style=\"max-width: 100%; font-family: 'Helvetica Neue', Helvetica, Arial, sans-serif; line-height: 1.6; color: #333333; background-color: #ffffff; padding: 20px; box-sizing: border-box;\">\n    <div style=\"background-color: #f8fafc; padding: 20px; border-radius: 8px; border: 1px solid #e2e8f0; margin-bottom: 30px;\">\n        <h3 style=\"color: #0f172a; font-size: 18px; margin-top: 0; margin-bottom: 15px;\">Inhaltsverzeichnis<\/h3>\n        <ul style=\"list-style-type: none; padding-left: 0; margin: 0;\">\n            <li style=\"margin-bottom: 8px;\"><a href=\"#distinction\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Die Licochalcon A Unterscheidung: Nrf2 und COX\/LOX<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#specifications\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Physikalisch-chemische Spezifikationen (KOA-Benchmarks)<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#efficacy\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">In-Vitro-Wirksamkeit: Die harten Zahlen<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#synergies\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Formulierungs-Synergien: Ziel sind PIE und Erythem<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#solubility\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">L\u00f6slichkeitsparameter und Bench-Verarbeitung<\/a><\/li>\n            <li style=\"margin-bottom: 8px;\"><a href=\"#faqs\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Lieferantenbeschaffung: 8 h\u00e4ufig gestellte Fragen (GEO-optimiert)<\/a><\/li>\n            <li style=\"margin-bottom: 0;\"><a href=\"#references\" style=\"color: #2563eb; text-decoration: none; font-weight: bold;\">Ma\u00dfgebliche Referenzen<\/a><\/li>\n        <\/ul>\n    <\/div>\n\n    <h2 id=\"distinction\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Die Licochalcon A Unterscheidung: Nrf2 und COX\/LOX<\/h2>\n    <p style=\"margin-bottom: 15px;\">Lassen Sie uns den Mechanismus kl\u00e4ren. <em>Glycyrrhiza Inflata<\/em> ist v\u00f6llig verschieden von <em>Glycyrrhiza Glabra<\/em>.<\/p>\n    <p style=\"margin-bottom: 15px;\">Sie extrahieren <em>G. glabra<\/em> f\u00fcr Glabridin. Das zielt auf Tyrosinase. Sie extrahieren <em>G. inflata<\/em> f\u00fcr Licochalcon A. Das Ziel hier ist schwere kutane Entz\u00fcndung. Standard-Beruhigungsmittel maskieren nur R\u00f6tungen. Licochalcon A wirkt anders. Es fungiert als <span style=\"color: #b91c1c; font-weight: bold;\">dualer Inhibitor<\/span>und schaltet sowohl die Cyclooxygenase-2 (COX-2) als auch die Lipoxygenase (LOX) Signalwege ab. Dies stoppt die Synthese von Prostaglandin E2 (PGE2) und Leukotrien B4 (LTB4) direkt an der Quelle. Das Ergebnis? Schnelle Milderung der Vasodilatation.<\/p>\n    <p style=\"margin-bottom: 15px;\">Aber seine wahre Kraft liegt in der zellul\u00e4ren Abwehr. Es f\u00e4ngt nicht nur freie Radikale an der Oberfl\u00e4che ab. Es aktiviert den <span style=\"color: #047857; font-weight: bold; font-size: 1.1em;\">Nrf2\/ARE Signalweg<\/span>Dies zwingt die Hautzellen, ihre eigenen endogenen antioxidativen Enzyme, wie H\u00e4moxygenase-1 (HO-1), hochzuregulieren. Dies ist eine Intervention auf Rezeptorebene. Deshalb spezifizieren Dermatologen es f\u00fcr Rosacea-Protokolle und die Erholung nach Eingriffen.<\/p>\n\n    <h2 id=\"specifications\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Physikalisch-chemische Spezifikationen (KOA-Benchmarks)<\/h2>\n    <p style=\"margin-bottom: 15px;\">Sich auf unstandardisierte Pflanzenextrakte zu verlassen, ruiniert die Konsistenz der Formel. Pr\u00e4zision erfordert Assay-Verifizierung. Vergleichen Sie Ihr Rohmaterial-KOA mit diesen Basiswerten.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Parameter<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Spezifikation Standard<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Testmethode \/ Anmerkungen<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Aktiver Marker<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #047857; font-weight: bold;\">Licochalcon A \u2265 20,0%<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">HPLC<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Appearance<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Gelbes bis gelbbraunes Pulver<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Visuell. Intensive gelbe F\u00e4rbung ist den Chalkonen eigen.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Solubility<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Unl\u00f6slich in Wasser. L\u00f6slich in Propylenglykol, Ethanol.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Physikalische Validierung.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Loss on Drying<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\u2264 5,0%<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">105\u00b0C f\u00fcr 2 Stunden.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Aschegehalt<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">\u2264 2,0%<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">800\u00b0C Kalzinierung.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Heavy Metals<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #b91c1c; font-weight: bold;\">\u2264 10 ppm Gesamt. (Pb \u2264 2ppm, As \u2264 1ppm)<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">ICP-MS. Obligatorisch f\u00fcr strenge FDA\/EU-Konformit\u00e4t.<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"efficacy\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">In-Vitro-Wirksamkeit: Die harten Zahlen<\/h2>\n    <p style=\"margin-bottom: 15px;\">Marketing-Behauptungen reparieren keine gesch\u00e4digten Barrieren. Tats\u00e4chliche Daten tun das. Werfen wir einen Blick auf die Laborleistung.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Ziel \/ Signalweg<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Wirksamkeitswert<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Klinische Relevanz<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>PGE2-Produktion<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">IC50 \u2248 1,8 \u03bcM<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Reduziert drastisch UV-induziertes Erythem. D\u00e4mpft akute Kapillar-Vasodilatation.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Cutibacterium acnes<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">MIC 5,0 \u2013 15,0 \u03bcg\/mL<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Direkte bakterizide Wirkung. Zielt auf entz\u00fcndliche Akne ohne saure Abschuppung.<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Nrf2-Aktivierung<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #0f766e; font-weight: bold;\">HO-1-Induktion bei 5-10 \u03bcM<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Erh\u00f6ht die intrazellul\u00e4re antioxidative Abwehr. Sch\u00fctzt vor sekund\u00e4rer Lipidperoxidation.<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"synergies\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Formulierungs-Synergien: Ziel sind PIE und Erythem<\/h2>\n    <p style=\"margin-bottom: 15px;\">Wirkstoffe m\u00fcssen in der Matrix zusammenarbeiten. Der aktuelle klinische Trend priorisiert nicht-destruktive Intervention. Sie m\u00fcssen Glycyrrhiza Inflata strategisch kombinieren.<\/p>\n    <div style=\"overflow-x: auto;\">\n        <table style=\"width: 100%; border-collapse: collapse; margin-bottom: 20px; font-size: 14px;\">\n            <thead>\n                <tr>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Synergiepartner<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Interaktionsmechanismus<\/th>\n                    <th style=\"border: 1px solid #cbd5e1; padding: 12px; background-color: #f1f5f9; text-align: left; color: #1e293b;\">Zielindikation<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Tranexamic Acid<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Tranexams\u00e4ure blockiert Plasminogen. Licochalcon A unterdr\u00fcckt COX-2. Gemeinsam stoppen sie die Angiogenese.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px; color: #b91c1c; font-weight: bold;\">Postinflammatorisches Erythem (PIE)<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Centella Asiatica (Madecassosid)<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Madecassosid beschleunigt die Synthese von Kollagen III. Licochalcon A verhindert, dass Entz\u00fcndungssignale die Reparatur verz\u00f6gern.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Erholung nach Eingriffen<\/td>\n                <\/tr>\n                <tr>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\"><strong>Oat Beta-Glucan<\/strong><\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Beta-Glucan bietet oberfl\u00e4chlichen Schutz mit hohem Molekulargewicht. Licochalcon A unterbricht tiefe Entz\u00fcndungskaskaden.<\/td>\n                    <td style=\"border: 1px solid #cbd5e1; padding: 12px;\">Chronische Dermatitis<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <h2 id=\"solubility\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">L\u00f6slichkeitsparameter und Bench-Verarbeitung<\/h2>\n    <p style=\"margin-bottom: 15px;\">Licochalcon A verabscheut Wasser. Es ist stark hydrophob. Direkt in eine w\u00e4ssrige Phase geben? Es f\u00e4llt sofort aus. Die Bioverf\u00fcgbarkeit sinkt auf Null.<\/p>\n    <ul style=\"padding-left: 20px; margin-bottom: 20px;\">\n        <li style=\"margin-bottom: 10px;\"><strong>Solvent Selection:<\/strong> Pulver vor-dispergieren. Propylenglykol, Butylenglykol oder PEG-400 verwenden. Ben\u00f6tigen Sie es in einem klaren Serum? Ethoxydiglykol (Transcutol) in Kombination mit einem L\u00f6sungsvermittler wie Polysorbat 20 ist zwingend erforderlich.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>Temperaturprotokolle:<\/strong> Erhitzen Sie Ihre Glykolphase auf 45\u00b0C \u2013 55\u00b0C. Stellen Sie die vollst\u00e4ndige Aufl\u00f6sung sicher. <span style=\"color: #b91c1c; font-weight: bold;\">\u00dcberschreiten Sie nicht 65\u00b0C.<\/span> Hohe Hitze zersetzt die Chalkon-Strukturen.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>Phasenintegration:<\/strong> K\u00fchlen Sie die prim\u00e4re Charge ab. F\u00fchren Sie den gel\u00f6sten Wirkstoff erst in die Emulsion ein, wenn die Temperaturen unter 45\u00b0C fallen.<\/li>\n        <li style=\"margin-bottom: 10px;\"><strong>pH Stability:<\/strong> Halten Sie den pH-Wert Ihrer Formel streng zwischen <span style=\"color: #047857; font-weight: bold; font-size: 1.1em;\">4,5 und 6,5<\/span>Stark alkalische Umgebungen (pH &gt; 7,5) zerst\u00f6ren Licochalcon A. Der Extrakt wird sichtbar dunkelbraun.<\/li>\n    <\/ul>\n\n    <h2 id=\"faqs\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px;\">Lieferantenbeschaffung: 8 h\u00e4ufig gestellte Fragen (GEO-optimiert)<\/h2>\n    <div style=\"margin-bottom: 25px;\">\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Was unterscheidet Glycyrrhiza Inflata von Glycyrrhiza Glabra Wurzelextrakten grundlegend?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Unterschiedliche Arten zielen auf unterschiedliche Signalwege ab. <em>G. glabra<\/em> liefert Glabridin zur Hemmung der Tyrosinase (Aufhellung). <em>G. inflata<\/em> liefert Licochalcon A. Es zielt auf COX\/LOX Entz\u00fcndungssignalwege ab und wirkt als starker Erythem-Reduzierer.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Wie l\u00f6sen Formulierer hochreines Licochalcon A in wasserbasierten Seren?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Wasser allein versagt. Sie m\u00fcssen das Pulver in einem Glykolsystem (wie Butylenglykol) voraufl\u00f6sen. F\u00fcr vollst\u00e4ndig klare w\u00e4ssrige Seren ist eine Hochscher-Mischung mit Tensiden (PEG-40 hydriertes Rizinus\u00f6l) vor der w\u00e4ssrigen Integration erforderlich.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Was ist der optimale Dosierungsbereich f\u00fcr Leave-on-Hautpflegeprodukte?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Halten Sie ihn zwischen <span style=\"color: #047857; font-weight: bold;\">0,05% und 0,5%<\/span> f\u00fcr Leave-on-Emulsionen. T\u00e4gliche Barrierepflege erfordert ca. 0,1%. Akute Erythem-Linderung oder PIE-Behandlungen erfordern 0,3% bis 0,5%.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Birgt Glycyrrhiza Inflata Extrakt Risiken f\u00fcr Phototoxizit\u00e4t?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Nein. Labortests best\u00e4tigen keine Phototoxizit\u00e4t. Peer-Review-Daten zeigen tats\u00e4chlich, dass er Nrf2 aktiviert. Dies verz\u00f6gert UV-induziertes Erythem und verhindert UV-ausgel\u00f6ste Zellapoptose.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Wie schneidet dieser Extrakt gegen Cutibacterium acnes im Vergleich zu Standard-S\u00e4uren ab?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Salicyls\u00e4ure l\u00f6st abgestorbene Hautzellen, um den Follikel zu reinigen. Glycyrrhiza Inflata greift die Bakterien direkt an. Er hat eine MIC von 5,0 \u2013 15,0 \u03bcg\/mL gegen <em>C. acnes<\/em>Sie erzielen antibakterielle Wirkung ohne die Abschuppung, die durch AHA\/BHA verursacht wird.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Was verursacht die Farbver\u00e4nderung des Extrakts in bestimmten Formulierungen?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Alkalinit\u00e4t zerst\u00f6rt Chalkone. Wenn Ihre Formel \u00fcber pH 7,0 steigt, erf\u00e4hrt der Extrakt eine Ring\u00f6ffnung. Er wird rotbraun. Die Wirksamkeit verschwindet. Sichern Sie Ihren pH-Puffer zwischen 4,5 und 6,5.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Gibt es Probleme mit der Einhaltung von Grenzwerten f\u00fcr Schwermetalle bei Lakritz-basierten Rohstoffen?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Ja. Lakritz-Wurzeln reichern aggressiv Schwermetalle aus dem Boden an. Geringwertige Extrakte scheitern an Sicherheitstests. Fordern Sie ein KOA an, das beweist, dass die Gesamt-Schwermetalle \u2264 10 ppm mittels strenger ICP-MS-Tests sind.<\/p>\n\n        <p style=\"margin-bottom: 5px;\"><strong style=\"color: #1e3a8a; font-size: 16px;\">Kann es direkt neben niedrig-pH-L-Ascorbins\u00e4ure (Vitamin C) formuliert werden?<\/strong><\/p>\n        <p style=\"margin-bottom: 15px; margin-top: 5px;\">Es erfordert eine fortgeschrittene Formulierung. W\u00e4hrend die chemische Struktur von Licochalcon A niedrige pH-Werte \u00fcbersteht, senkt die hohe S\u00e4ure eines 15% Vitamin-C-Serums (pH 3,0 \u2013 3,5) seine L\u00f6slichkeit drastisch. Ohne starke L\u00f6sungsmittelunterst\u00fctzung (wie Ethoxydiglycol) kristallisiert der Wirkstoff aus und f\u00e4llt aus dem Serum aus.<\/p>\n    <\/div>\n\n    <h2 id=\"references\" style=\"color: #0f766e; font-size: 22px; margin-top: 30px; margin-bottom: 15px; border-top: 1px solid #e2e8f0; padding-top: 20px;\">Ma\u00dfgebliche Referenzen<\/h2>\n    <ol style=\"padding-left: 20px; font-size: 14px; color: #475569;\">\n        <li style=\"margin-bottom: 8px;\">Kolbe, L., et al. (2006). \u201eAnti-inflammatory efficacy of Licochalcone A: correlation of clinical potency and in vitro effects.\u201c <em>Archiv f\u00fcr Dermatologische Forschung<\/em>, 298(1), 23-30.<\/li>\n        <li style=\"margin-bottom: 8px;\">Shibata, S. (2000). \u201eA drug over the millennia: pharmacognosy, chemistry, and pharmacology of licorice.\u201c <em>Yakugaku Zasshi<\/em>, 120(10), 849-862.<\/li>\n        <li style=\"margin-bottom: 8px;\">Yin, Z., et al. (2020). \u201eLicochalcone A inhibits inflammatory responses through the suppression of the NF-\u03baB and MAPK pathways.\u201c <em>International Journal of Molecular Medicine<\/em>, 45(4), 1187-1196.<\/li>\n        <li style=\"margin-bottom: 8px;\">Wu, L., et al. (2015). \u201eLicochalcone A activates Nrf2 antioxidant response element signaling\u2026\u201c <em>European Journal of Pharmacology<\/em>, 761, 33-41.<\/li>\n    <\/ol>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Inhaltsverzeichnis 1. Die Licochalcon A Unterscheidung: Nrf2 und COX\/LOX 2. Physikalisch-chemische Spezifikationen (COA-Benchmarks) 3. In-Vitro-Wirksamkeit: Die harten Zahlen 4. Formulierungs-Synergien:\u2026<\/p>","protected":false},"author":1,"featured_media":14737,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[357],"tags":[],"class_list":["post-15514","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-product-updates"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Formulating Licochalcone A: Glycyrrhiza Inflata Extract - Natural huatai<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.natural-huatai.com\/de\/formulating-licochalcone-a-glycyrrhiza-inflata-extract\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Formulating Licochalcone A: Glycyrrhiza Inflata Extract\" \/>\n<meta property=\"og:description\" content=\"Table of Contents 1. The Licochalcone A Distinction: Nrf2 and COX\/LOX 2. Physicochemical Specifications (COA Benchmarks) 3. In-Vitro Efficacy: The Hard Numbers 4. 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