Hydrolyzed Sodium Hyaluronate
Ultra-Low Molecular Weight Enzymatic Technology for Superior Transdermal Absorption
While traditional Hyaluronic Acid sits on the skin surface to provide hydration, Hydrolyzed Sodium Hyaluronate is engineered for depth. Utilizing advanced enzymatic cleavage technology by Shaanxi Huatai Bio-fine Chemical Co., we have reduced the molecular weight to below 10,000 Daltons. This “ultra-mini” size allows the molecules to bypass the stratum corneum and penetrate deep into the dermis. It is not just a humectant; it is a bioactive signal that rehydrates the skin from within, repairs damaged cells, and significantly enhances the efficacy of co-formulated actives.
| CAS No. | 9067-32-7 |
|---|---|
| Source | Microbial Fermentation with Specialized Enzymatic Cleavage |
| Appearance Color | White to Off-white Powder |
| Key Parameter | Molecular Weight < 10,000 Daltons / Purity >= 95.0% |
| Solubility | Highly Water-soluble |
1. Technical Specifications & Market Edge
| Technical Attribute | Huatai Premium Standard | Competitive Advantage |
| Molecular Weight | < 10,000 Daltons (Ultra-Low) | Achieves significantly deeper dermal penetration than conventional “Low MW” Hyaluronic Acid. |
| Transdermal Absorption | Rapid Flux Rate | Permeates the skin barrier and reaches the dermal layer within minutes of application. |
| Manufacturing Process | Precision Enzymatic Cleavage | Preserves the exact molecular structure without relying on harsh chemical degradation. |
| Biological Activity | Cellular Signaling Agent | Acts as a biological trigger to stimulate the body’s internal synthesis of native HA. |
| Purity Level (HPLC) | ≥ 95.0% | Features negligible protein residue, ensuring exceptional tolerance for sensitive skin. |
| Sensory Profile | Water-Light / Zero Tack | Leaves absolutely no sticky residue; feels indistinguishable from fresh water upon contact. |
2. Biological Mechanisms of Action
Our Hydrolyzed Sodium Hyaluronate targets skin aging and dehydration through three distinct physiological pathways:
| Physiological Pathway | Biological Effect |
| Profound Dermal Irrigation | Its micro-size allows it to navigate between cells effortlessly, delivering targeted hydration to the deep epidermis and dermis to plump tissue from within. |
| Cellular Activation & Repair | Functions as a signaling molecule to engage fibroblast CD44 receptors, boosting the natural production of endogenous HA and Type I Collagen. |
| Free Radical Neutralization | Actively scavenges internal Reactive Oxygen Species (ROS) generated by UV exposure, defending deep tissue against photo-induced aging. |
3. Formulation & Processing Directives
| Formulation Parameter | Recommendation | Application Note |
| Standard Dosage | 0.1% to 1.0% | Highly effective baseline; frequently serves as the primary “hero” hydrating active. |
| Intensive Treatments | Up to 2.0% | The optimal concentration for clinical-grade serums and intensive deep-repair ampoules. |
| Optimal pH Window | 4.0 to 8.0 | Demonstrates exceptional structural stability across both neutral and acidic formulations. |
| Thermal Resilience | Process Below 80°C | Exhibits excellent heat tolerance; can be seamlessly incorporated during most production phases. |
| Formulation Synergy | Delivery Enhancer | Acts as a carrier vehicle to help drive larger active molecules deeper into the skin layers. |
4. Strategic Market Positioning & Ingredient Synergies
Commercial Positioning:
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Advanced Hydration Narrative: Captures educated consumers seeking deep, long-term anti-aging benefits that go beyond temporary surface moisture.
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Formulation Versatility: The ultra-light, watery texture is impeccable for refreshing essence-toners, weightless serums, and light O/W emulsions where heaviness is a negative.
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Clinical & Aesthetic Integration: A vital, high-performance component for post-laser or post-microneedling regimens, offering immediate deep-tissue moisture replenishment.
High-Performance Synergistic Blends:
| Synergistic Combination | Targeted Outcome |
| Hydrolyzed HA + Sodium DNA (PDRN) | Delivers a holistic “Inside-Out” rejuvenation strategy, pairing deep moisture with cellular DNA-level repair. |
| Hydrolyzed HA + Retinal | Infuses the skin with profound hydration to effectively counteract the flakiness and dryness typically induced by Vitamin A derivatives. |
| Hydrolyzed HA + High MW HA | The “Full-Spectrum” hydration matrix: High MW seals the skin’s surface, while Ultra-Low MW plumps from the dermal foundation. |
5. Quality Control & Regulatory Compliance
| Compliance Area | Assurance Details |
| Manufacturing Standards | Synthesized in state-of-the-art facilities adhering strictly to ISO 9001 and ISO 22000 certifications. |
| Regulatory Documentation | Fully supported by comprehensive COAs, MSDS, and Technical Data Sheets (TDS) to substantiate global compliance and transdermal efficacy claims. |
| Ideal Product Formats | The ingredient of choice for deep-penetrating essences, premium regenerative sheet masks, moisture-rich toners, and anti-aging ampoules. |
6. Collaborate with Shaanxi Huatai Bio-fine Chemical Co.
Upgrade your next formulation with our ultra-low molecular weight technology.
| Service Offering | Actionable Step |
| Access Technical Data | Request our comprehensive dossier to review precise transdermal penetration studies and MW analytics. |
| Evaluate Samples | Claim a complimentary sample to physically witness the immediate, water-like absorption of our <10k Da HA. |
| Bespoke Procurement | Contact our technical sales team for custom volume pricing and tailored molecular weight specifications for your brand. |
As a premier Hydrolyzed Sodium Hyaluronate Manufacturer in China, we provide high-purity Cosmetic Grade Hydrolyzed Sodium Hyaluronate designed to empower innovative formulations. Our Hydrolyzed Sodium Hyaluronate factory is dedicated to a consistent Bulk supply of Hydrolyzed Sodium Hyaluronate, serving as a reliable Hydrolyzed Sodium Hyaluronate Wholesaler and Supplier for leading global brands. Whether you are optimizing existing formulas or seeking a competitive Hydrolyzed Sodium Hyaluronate Price for large-scale production, our Hydrolyzed Sodium Hyaluronate Active Ingredients offer the quality and stability your brand deserves. Integrate the finest Hydrolyzed Sodium Hyaluronate Skincare Ingredients into your laboratory today.
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