Sodium Hyaluronate (Low MW)
Low Molecular Weight (LMW) Sodium Hyaluronate (below 50 kDa) is scientifically engineered to maximize skin penetration and act at the dermal-epidermal junction. Unlike high MW HA that primarily moisturizes the surface, LMW HA delivers deep, sustained hydration, promotes the synthesis of native Hyaluronic Acid, and supports the skin’s viscoelastic properties and internal structure, leading to reduced wrinkle depth and improved firmness.
| INCI Name | Sodium Hyaluronate |
|---|---|
| CAS No. | 9067-32-7 |
| Molecular Weight | Low Molecular Weight (e.g., 10 kDa – 50 kDa) |
| Source | Biotechnological Fermentation (Non-animal origin) |
| Core Function | Deep Hydration, Wrinkle Reduction, Elasticity Improvement, Transdermal Penetration. |
1. Product Overview: The Dermal Hydration Architect
Shaanxi Huatai Bio-fine Chemical Co. provides premium-grade Low Molecular Weight (LMW) Sodium Hyaluronate (10–50 kDa), the definitive active for multi-layer hydration architectures. Unlike High MW variants that primarily provide surface-level film formation, our LMW HA is engineered for deep epidermal and dermal penetration. It serves as a biological “plumping agent,” crossing the stratum corneum to replace age-related hyaluronic acid loss and trigger intracellular signaling. This is the gold-standard active for luxury serums and clinical-grade anti-aging treatments requiring measurable, deep-tissue water retention and wrinkle-depth reduction.
Core Features & Primary Benefits:
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Deep-Dermal Bio-Availability: Precisely sized (10–50 kDa) to bypass the epidermal barrier, delivering moisture-binding capacity to the lower layers where fine lines originate.
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Intracellular Signaling (CD44 Interaction): Effectively interacts with skin cell surface receptors (CD44), modulating the skin’s natural ability to synthesize endogenous hyaluronic acid and structural matrix proteins.
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Deep-Plumping Efficacy: By drawing moisture into the dermal matrix, it physically “fills” wrinkles and fine lines from within, providing a sustained anti-aging effect that surface humectants cannot replicate.
2. Technical Specifications & Quality Parameters
| Technical Attribute | Shaanxi Huatai Premium Standard | Competitive Advantage |
| Material Identity | Sodium Hyaluronate (LMW) | Bio-available, deep-penetrating glycosaminoglycan. |
| Molecular Weight | 10 kDa – 50 kDa | Targeted range for maximal epidermal permeation without inflammatory signaling. |
| Assay Purity | ≥ 95.0% | Ultra-high purity ensures non-irritating performance. |
| Viscosity Impact | Low | Allows for elegant, low-viscosity serum architectures and mists. |
| Regulatory Standing | COSMOS/HALAL Certified | Complies with the strictest international clean-label standards. |
3. Biological Mechanisms of Action
Our LMW Sodium Hyaluronate rejuvenates skin integrity through three key pathways:
| Action Pathway | Biological Impact |
| Intercellular Permeation | Navigates the intercorneocyte spaces to reach the living epidermis, bypassing the “film-only” limitations of traditional HA. |
| Receptor-Mediated Signaling | Binds to CD44 receptors to stimulate natural hyaluronic acid production and dampen pro-inflammatory triggers. |
| Matrix Volumization | Increases dermal water volume, physically expanding the extracellular matrix to reduce the visible depth of lines and wrinkles. |
4. Formulation & Processing Directives
| Formulation Parameter | Recommendation | Application Note |
| Suggested Dosage | 0.01% – 0.5% (Pure Powder) | Highly potent; even at low inclusion rates, it provides profound deep-dermal plumping. |
| Processing Instructions | Aqueous Phase Integration | Fully water-soluble; add slowly to the aqueous phase under moderate, uniform shear mixing. |
| Stability/Temperature | Stable (<40°C Addition) | While thermally stable, incorporation during cooling preserves the delicate consistency of the final product. |
| pH Compatibility | 5.0 – 8.0 | Robust across standard skincare ranges; requires no specialized stabilization for standard formulations. |
5. Strategic Market Positioning & Ingredient Synergies
Commercial Positioning:
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The “Deep-Hydration” Narrative: Positions your brand as a “science-first” expert, differentiating your product from surface-only hyaluronic moisturizers.
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Clinical Anti-Aging: Essential for “Resurfacing” and “Anti-Wrinkle” claims, providing the structural foundation that external anti-aging actives (like Retinol or AHAs) need to function effectively.
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Multi-Molecular Authority: The essential base layer in a “Multi-Weight HA Matrix,” allowing your brand to claim “total-spectrum” hydration.
High-Performance Synergistic Blends:
| Synergistic Pairing | Targeted Formulation Benefit |
| LMW HA + HMW HA | The “Total-Hydration” Matrix—HMW for surface film-protection; LMW for deep dermal volumization. |
| LMW HA + Ectoin | Fuses deep-dermal moisture saturation with an extreme-environment barrier shield. |
| LMW HA + PDRN (Sodium DNA) | Combines internal hydration-plumping with nucleotide-level tissue repair for extreme age-reversal. |
6. Quality Control & Regulatory Compliance
| Compliance Area | Assurance Details |
| Manufacturing Accreditations | Synthesized under uncompromising quality control protocols within ISO 9001, ISO 22000, and HALAL certified facilities. |
| Eco-Ethical Standards | Adheres strictly to COSMOS standards, verifying our raw materials align with natural, organic, and clean-label cosmetic criteria. |
| Regulatory Documentation | Every batch is accompanied by a full technical dossier, including COAs, TDS, and MSDS. |
7. Collaborate with Shaanxi Huatai Bio-fine Chemical Co.
Upgrade your hydration and anti-aging lines with our ultra-pure LMW Sodium Hyaluronate technology.
| Service Offering | Actionable Step |
| Access Technical Data | Request our complete dossier detailing permeation studies (vs. HMW HA), wrinkle-volume reduction data, and CD44-signaling efficacy. |
| Evaluate Samples | Claim a complimentary sample to directly evaluate the superior purity and dispersion performance of our LMW Sodium Hyaluronate. |
| Bespoke Procurement | Contact our technical sales team for factory-direct bulk pricing and specialized guidance on your multi-molecular HA formulation architecture. |
As a premier Sodium Hyaluronate (Low MW) Manufacturer in China, we provide high-purity Cosmetic Grade Sodium Hyaluronate (Low MW) designed to empower innovative formulations. Our Sodium Hyaluronate (Low MW) factory is dedicated to a consistent Bulk supply of Sodium Hyaluronate (Low MW), serving as a reliable Sodium Hyaluronate (Low MW) Wholesaler and Supplier for leading global brands. Whether you are optimizing existing formulas or seeking a competitive Sodium Hyaluronate (Low MW) Price for large-scale production, our Sodium Hyaluronate (Low MW) Active Ingredients offer the quality and stability your brand deserves. Integrate the finest Sodium Hyaluronate (Low MW) Skincare Ingredients into your laboratory today.
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